| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DLG3 | NEDD4 | ENSPTRP00000069805 | ENSPTRP00000085467 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | NEDD4 E3 ubiquitin protein ligase. | 0.929 |
| DLG3 | NEDD4L | ENSPTRP00000069805 | ENSPTRP00000062932 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | NEDD4L isoform 6. | 0.930 |
| NEDD4 | DLG3 | ENSPTRP00000085467 | ENSPTRP00000069805 | NEDD4 E3 ubiquitin protein ligase. | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | 0.929 |
| NEDD4 | NEDD4L | ENSPTRP00000085467 | ENSPTRP00000062932 | NEDD4 E3 ubiquitin protein ligase. | NEDD4L isoform 6. | 0.965 |
| NEDD4 | SCNN1A | ENSPTRP00000085467 | ENSPTRP00000064198 | NEDD4 E3 ubiquitin protein ligase. | Amiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. | 0.961 |
| NEDD4 | SCNN1B | ENSPTRP00000085467 | ENSPTRP00000013457 | NEDD4 E3 ubiquitin protein ligase. | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | 0.966 |
| NEDD4 | SCNN1G | ENSPTRP00000085467 | ENSPTRP00000013456 | NEDD4 E3 ubiquitin protein ligase. | Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. | 0.929 |
| NEDD4 | SGK1 | ENSPTRP00000085467 | ENSPTRP00000085488 | NEDD4 E3 ubiquitin protein ligase. | Non-specific serine/threonine protein kinase. | 0.831 |
| NEDD4 | SMAD3 | ENSPTRP00000085467 | ENSPTRP00000090625 | NEDD4 E3 ubiquitin protein ligase. | Mothers against decapentaplegic homolog. | 0.838 |
| NEDD4 | SMAD7 | ENSPTRP00000085467 | ENSPTRP00000017016 | NEDD4 E3 ubiquitin protein ligase. | Mothers against decapentaplegic homolog. | 0.866 |
| NEDD4 | UBC | ENSPTRP00000085467 | ENSPTRP00000050925 | NEDD4 E3 ubiquitin protein ligase. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.953 |
| NEDD4L | DLG3 | ENSPTRP00000062932 | ENSPTRP00000069805 | NEDD4L isoform 6. | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | 0.930 |
| NEDD4L | NEDD4 | ENSPTRP00000062932 | ENSPTRP00000085467 | NEDD4L isoform 6. | NEDD4 E3 ubiquitin protein ligase. | 0.965 |
| NEDD4L | SCNN1A | ENSPTRP00000062932 | ENSPTRP00000064198 | NEDD4L isoform 6. | Amiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. | 0.996 |
| NEDD4L | SCNN1B | ENSPTRP00000062932 | ENSPTRP00000013457 | NEDD4L isoform 6. | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | 0.997 |
| NEDD4L | SCNN1G | ENSPTRP00000062932 | ENSPTRP00000013456 | NEDD4L isoform 6. | Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. | 0.993 |
| NEDD4L | SFN | ENSPTRP00000062932 | ENSPTRP00000056936 | NEDD4L isoform 6. | SFN isoform 1; Belongs to the 14-3-3 family. | 0.937 |
| NEDD4L | SGK1 | ENSPTRP00000062932 | ENSPTRP00000085488 | NEDD4L isoform 6. | Non-specific serine/threonine protein kinase. | 0.997 |
| NEDD4L | SMAD3 | ENSPTRP00000062932 | ENSPTRP00000090625 | NEDD4L isoform 6. | Mothers against decapentaplegic homolog. | 0.914 |
| NEDD4L | SMAD7 | ENSPTRP00000062932 | ENSPTRP00000017016 | NEDD4L isoform 6. | Mothers against decapentaplegic homolog. | 0.972 |
