STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSME3-2Proteasome activator subunit 3. (265 aa)    
Predicted Functional Partners:
PSME1
Proteasome (Prosome, macropain) activator subunit 1 (PA28 alpha).
  
 
0.944
PSMD14
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14.
   
 0.928
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity).
   
 
 0.919
PSME2
Proteasome (Prosome, macropain) activator subunit 2 (PA28 beta).
  
 
0.910
RXRA
Retinoid X receptor, alpha.
   
  0.903
NR1H3
Nuclear receptor subfamily 1 group H member 3.
   
  0.903
PSMB10
Proteasome subunit beta type-10.
   
 0.840
PSMC5
Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family.
   
 0.819
FAM192A
FAM192A isoform 17.
    
 
 0.803
ENSPTRP00000080351
annotation not available
    
 
 0.803
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.