STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPTRP00000065151annotation not available (415 aa)    
Predicted Functional Partners:
TINF2
TERF1-interacting nuclear factor 2.
    
 0.885
ACD
ACD isoform 1.
    
 0.874
TERF2IP
Telomeric repeat binding factor 2, interacting protein.
    
 0.845
POT1
Protection of telomeres 1 homolog.
    
 0.820
CK820_G0011712
POT1 isoform 12.
    
 0.820
TERF2
Telomeric repeat binding factor 2.
    
0.793
CTC1
CTS telomere maintenance complex component 1.
     
 0.725
TERB1
Telomere repeat binding bouquet formation protein 1.
    
 0.716
TEN1
Chromosome 17 open reading frame 106.
     
 0.680
STN1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
    
 0.612
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.