STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRED2SPRED2 isoform 3. (432 aa)    
Predicted Functional Partners:
SPRED1
Sprouty-related, EVH1 domain containing 1.
  
  
0.900
NF1
Neurofibromin 1.
    
 0.878
SPATA5
Spermatogenesis associated 5.
    
 
 0.634
NUDT6
Nudix hydrolase 6.
      
 0.626
KIT
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.612
NBR1
NBR1 isoform 1.
    
 
 0.600
FGFRL1
Fibroblast growth factor receptor-like 1.
     
 0.585
STAM
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.
      
 0.578
STAM2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
      
 0.577
NEK2
NIMA (Never in mitosis gene a)-related kinase 2.
    
 0.534
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.