| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BIRC2 | BIRC3 | ENSPTRP00000007251 | ENSPTRP00000090891 | Baculoviral IAP repeat containing 2. | Baculoviral IAP repeat containing 3. | 0.974 |
| BIRC2 | FADD | ENSPTRP00000007251 | ENSPTRP00000006883 | Baculoviral IAP repeat containing 2. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.955 |
| BIRC2 | IKBKB | ENSPTRP00000007251 | ENSPTRP00000034600 | Baculoviral IAP repeat containing 2. | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. | 0.786 |
| BIRC2 | LTA | ENSPTRP00000007251 | ENSPTRP00000030651 | Baculoviral IAP repeat containing 2. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | 0.487 |
| BIRC2 | RIPK1 | ENSPTRP00000007251 | ENSPTRP00000030180 | Baculoviral IAP repeat containing 2. | Receptor (TNFRSF)-interacting serine-threonine kinase 1. | 0.997 |
| BIRC2 | TNF | ENSPTRP00000007251 | ENSPTRP00000069905 | Baculoviral IAP repeat containing 2. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.971 |
| BIRC2 | TNFRSF1A | ENSPTRP00000007251 | ENSPTRP00000066030 | Baculoviral IAP repeat containing 2. | Tumor necrosis factor receptor superfamily, member 1A. | 0.997 |
| BIRC2 | TRADD | ENSPTRP00000007251 | ENSPTRP00000046129 | Baculoviral IAP repeat containing 2. | TNFRSF1A-associated via death domain. | 0.994 |
| BIRC2 | TRAF2 | ENSPTRP00000007251 | ENSPTRP00000036949 | Baculoviral IAP repeat containing 2. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.997 |
| BIRC3 | BIRC2 | ENSPTRP00000090891 | ENSPTRP00000007251 | Baculoviral IAP repeat containing 3. | Baculoviral IAP repeat containing 2. | 0.974 |
| BIRC3 | FADD | ENSPTRP00000090891 | ENSPTRP00000006883 | Baculoviral IAP repeat containing 3. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.941 |
| BIRC3 | IKBKB | ENSPTRP00000090891 | ENSPTRP00000034600 | Baculoviral IAP repeat containing 3. | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. | 0.815 |
| BIRC3 | LTA | ENSPTRP00000090891 | ENSPTRP00000030651 | Baculoviral IAP repeat containing 3. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | 0.475 |
| BIRC3 | RIPK1 | ENSPTRP00000090891 | ENSPTRP00000030180 | Baculoviral IAP repeat containing 3. | Receptor (TNFRSF)-interacting serine-threonine kinase 1. | 0.996 |
| BIRC3 | TNF | ENSPTRP00000090891 | ENSPTRP00000069905 | Baculoviral IAP repeat containing 3. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.933 |
| BIRC3 | TNFRSF1A | ENSPTRP00000090891 | ENSPTRP00000066030 | Baculoviral IAP repeat containing 3. | Tumor necrosis factor receptor superfamily, member 1A. | 0.997 |
| BIRC3 | TRADD | ENSPTRP00000090891 | ENSPTRP00000046129 | Baculoviral IAP repeat containing 3. | TNFRSF1A-associated via death domain. | 0.975 |
| BIRC3 | TRAF2 | ENSPTRP00000090891 | ENSPTRP00000036949 | Baculoviral IAP repeat containing 3. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.996 |
| FADD | BIRC2 | ENSPTRP00000006883 | ENSPTRP00000007251 | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | Baculoviral IAP repeat containing 2. | 0.955 |
| FADD | BIRC3 | ENSPTRP00000006883 | ENSPTRP00000090891 | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | Baculoviral IAP repeat containing 3. | 0.941 |
