STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM6Tripartite motif containing 6. (841 aa)    
Predicted Functional Partners:
OR52H1
Olfactory receptor.
      
 0.655
TRAT1
T cell receptor associated transmembrane adaptor 1.
      
 0.570
BBOX1
Gamma-butyrobetaine hydroxylase 1.
      
 0.504
TRIM5
Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...]
  
 
0.464
UBQLN1
UBQLN1 isoform 1.
    
 0.455
UBQLN3
UBQLN3 isoform 1.
    
 0.455
TRIM37
Tripartite motif-containing 37.
    
 
 0.450
PNRC1
Proline-rich nuclear receptor coactivator 1.
      
 0.448
LOC470275
APOBEC3F isoform 1.
  
  
 0.432
APOBEC3D
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D.
  
  
 0.424
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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