CNN2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CNN2

CNN2 isoform 9. (148 aa)

Predicted Functional Partners:

CK820_G0051333

0.722

WDR90

0.608

WDR1

0.477

VCL

0.461

EFHB

0.454

TLN1

0.433

FLNA

0.421

TLN2

0.414

TUBAL3

0.402

ENSPTRP00000008373

0.402

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CK820_G0051333	CNN2	ENSPTRP00000077394	ENSPTRP00000067670	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	CNN2 isoform 9.	0.722
CK820_G0051333	EFHB	ENSPTRP00000077394	ENSPTRP00000025326	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	EF-hand domain family member B.	0.454
CK820_G0051333	ENSPTRP00000008373	ENSPTRP00000077394	ENSPTRP00000008373	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	annotation not available	0.402
CK820_G0051333	FLNA	ENSPTRP00000077394	ENSPTRP00000063420	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	FLNA isoform 8.	0.421
CK820_G0051333	TLN1	ENSPTRP00000077394	ENSPTRP00000071704	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	TLN1 isoform 1.	0.433
CK820_G0051333	TLN2	ENSPTRP00000077394	ENSPTRP00000012209	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	TLN2 isoform 1.	0.414
CK820_G0051333	TUBAL3	ENSPTRP00000077394	ENSPTRP00000003816	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.402
CK820_G0051333	VCL	ENSPTRP00000077394	ENSPTRP00000004598	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	VCL isoform 2.	0.461
CK820_G0051333	WDR1	ENSPTRP00000077394	ENSPTRP00000027418	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	WD repeat domain 1.	0.477
CK820_G0051333	WDR90	ENSPTRP00000077394	ENSPTRP00000079002	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	WDR90 isoform 1.	0.608
CNN2	CK820_G0051333	ENSPTRP00000067670	ENSPTRP00000077394	CNN2 isoform 9.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.722
CNN2	EFHB	ENSPTRP00000067670	ENSPTRP00000025326	CNN2 isoform 9.	EF-hand domain family member B.	0.454
CNN2	ENSPTRP00000008373	ENSPTRP00000067670	ENSPTRP00000008373	CNN2 isoform 9.	annotation not available	0.402
CNN2	FLNA	ENSPTRP00000067670	ENSPTRP00000063420	CNN2 isoform 9.	FLNA isoform 8.	0.421
CNN2	TLN1	ENSPTRP00000067670	ENSPTRP00000071704	CNN2 isoform 9.	TLN1 isoform 1.	0.433
CNN2	TLN2	ENSPTRP00000067670	ENSPTRP00000012209	CNN2 isoform 9.	TLN2 isoform 1.	0.414
CNN2	TUBAL3	ENSPTRP00000067670	ENSPTRP00000003816	CNN2 isoform 9.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.402
CNN2	VCL	ENSPTRP00000067670	ENSPTRP00000004598	CNN2 isoform 9.	VCL isoform 2.	0.461
CNN2	WDR1	ENSPTRP00000067670	ENSPTRP00000027418	CNN2 isoform 9.	WD repeat domain 1.	0.477
CNN2	WDR90	ENSPTRP00000067670	ENSPTRP00000079002	CNN2 isoform 9.	WDR90 isoform 1.	0.608