BCL6 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	BCOR	ENSPTRP00000068244	ENSPTRP00000037403	BCL6 transcription repressor.	BCL6 corepressor.	0.900
BCL6	BCOR-2	ENSPTRP00000068244	ENSPTRP00000078038	BCL6 transcription repressor.	BCL6 corepressor.	0.900
BCL6	CD4	ENSPTRP00000068244	ENSPTRP00000054833	BCL6 transcription repressor.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.843
BCL6	CXCR5	ENSPTRP00000068244	ENSPTRP00000073048	BCL6 transcription repressor.	C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	0.835
BCL6	FOXP3	ENSPTRP00000068244	ENSPTRP00000037587	BCL6 transcription repressor.	FOXP3 isoform 4.	0.808
BCL6	HDAC1	ENSPTRP00000068244	ENSPTRP00000075891	BCL6 transcription repressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.812
BCL6	IRF4	ENSPTRP00000068244	ENSPTRP00000030162	BCL6 transcription repressor.	Interferon regulatory factor 4.	0.907
BCL6	LOC748850	ENSPTRP00000068244	ENSPTRP00000067224	BCL6 transcription repressor.	HDAC2 isoform 9.	0.812
BCL6	NCOR1	ENSPTRP00000068244	ENSPTRP00000075557	BCL6 transcription repressor.	Nuclear receptor corepressor 1.	0.850
BCL6	NCOR2	ENSPTRP00000068244	ENSPTRP00000088620	BCL6 transcription repressor.	Nuclear receptor corepressor 2.	0.932
BCOR	BCL6	ENSPTRP00000037403	ENSPTRP00000068244	BCL6 corepressor.	BCL6 transcription repressor.	0.900
BCOR	HDAC1	ENSPTRP00000037403	ENSPTRP00000075891	BCL6 corepressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.461
BCOR	LOC748850	ENSPTRP00000037403	ENSPTRP00000067224	BCL6 corepressor.	HDAC2 isoform 9.	0.461
BCOR-2	BCL6	ENSPTRP00000078038	ENSPTRP00000068244	BCL6 corepressor.	BCL6 transcription repressor.	0.900
BCOR-2	HDAC1	ENSPTRP00000078038	ENSPTRP00000075891	BCL6 corepressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.461
BCOR-2	LOC748850	ENSPTRP00000078038	ENSPTRP00000067224	BCL6 corepressor.	HDAC2 isoform 9.	0.461
CD4	BCL6	ENSPTRP00000054833	ENSPTRP00000068244	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	BCL6 transcription repressor.	0.843
CD4	CXCR5	ENSPTRP00000054833	ENSPTRP00000073048	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	0.915
CD4	FOXP3	ENSPTRP00000054833	ENSPTRP00000037587	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	FOXP3 isoform 4.	0.959
CD4	HDAC1	ENSPTRP00000054833	ENSPTRP00000075891	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.446