CK820_G0014442 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CK820_G0014442

PRSS3 isoform 6; Belongs to the peptidase S1 family. (268 aa)

Predicted Functional Partners:

SPINT2

0.854

APP

0.851

AMBP

0.850

TFPI

0.840

APLP2

0.830

SPINK1

0.603

CTRB2

0.547

CTRL

0.542

LOC736783

0.530

MST1R

0.505

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBP	CK820_G0014442	ENSPTRP00000036355	ENSPTRP00000068597	Alpha-1-microglobulin/bikunin precursor.	PRSS3 isoform 6; Belongs to the peptidase S1 family.	0.850
APLP2	APP	ENSPTRP00000007666	ENSPTRP00000093932	Amyloid beta precursor like protein 2.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.654
APLP2	CK820_G0014442	ENSPTRP00000007666	ENSPTRP00000068597	Amyloid beta precursor like protein 2.	PRSS3 isoform 6; Belongs to the peptidase S1 family.	0.830
APP	APLP2	ENSPTRP00000093932	ENSPTRP00000007666	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor like protein 2.	0.654
APP	CK820_G0014442	ENSPTRP00000093932	ENSPTRP00000068597	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	PRSS3 isoform 6; Belongs to the peptidase S1 family.	0.851
APP	CTRB2	ENSPTRP00000093932	ENSPTRP00000072677	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Chymotrypsinogen B2.	0.559
APP	CTRL	ENSPTRP00000093932	ENSPTRP00000014084	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Chymotrypsin like; Belongs to the peptidase S1 family.	0.597
APP	LOC736783	ENSPTRP00000093932	ENSPTRP00000040711	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Chymotrypsinogen B2.	0.543
APP	SPINT2	ENSPTRP00000093932	ENSPTRP00000065532	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	T0106202 isoform 2.	0.439
CK820_G0014442	AMBP	ENSPTRP00000068597	ENSPTRP00000036355	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Alpha-1-microglobulin/bikunin precursor.	0.850
CK820_G0014442	APLP2	ENSPTRP00000068597	ENSPTRP00000007666	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Amyloid beta precursor like protein 2.	0.830
CK820_G0014442	APP	ENSPTRP00000068597	ENSPTRP00000093932	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.851
CK820_G0014442	CTRB2	ENSPTRP00000068597	ENSPTRP00000072677	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Chymotrypsinogen B2.	0.547
CK820_G0014442	CTRL	ENSPTRP00000068597	ENSPTRP00000014084	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Chymotrypsin like; Belongs to the peptidase S1 family.	0.542
CK820_G0014442	LOC736783	ENSPTRP00000068597	ENSPTRP00000040711	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Chymotrypsinogen B2.	0.530
CK820_G0014442	MST1R	ENSPTRP00000068597	ENSPTRP00000025788	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.505
CK820_G0014442	SPINK1	ENSPTRP00000068597	ENSPTRP00000029708	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Serine peptidase inhibitor, Kazal type 1.	0.603
CK820_G0014442	SPINT2	ENSPTRP00000068597	ENSPTRP00000065532	PRSS3 isoform 6; Belongs to the peptidase S1 family.	T0106202 isoform 2.	0.854
CK820_G0014442	TFPI	ENSPTRP00000068597	ENSPTRP00000021752	PRSS3 isoform 6; Belongs to the peptidase S1 family.	Tissue factor pathway inhibitor.	0.840
CTRB2	APP	ENSPTRP00000072677	ENSPTRP00000093932	Chymotrypsinogen B2.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.559