ERBB2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	EGFR	ENSPTRP00000028112	ENSPTRP00000069741	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	ERBB2	ENSPTRP00000028112	ENSPTRP00000069840	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.996
EGF	ERBB3	ENSPTRP00000028112	ENSPTRP00000008639	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian).	0.992
EGF	ERBB4	ENSPTRP00000028112	ENSPTRP00000063299	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.974
EGF	GRB2	ENSPTRP00000028112	ENSPTRP00000016382	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Growth factor receptor-bound protein 2.	0.748
EGF	NRG1	ENSPTRP00000028112	ENSPTRP00000092088	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	NRG1 isoform 3.	0.768
EGF	PIK3CA	ENSPTRP00000028112	ENSPTRP00000084763	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.832
EGF	PIK3R1	ENSPTRP00000028112	ENSPTRP00000076964	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha).	0.674
EGF	SHC1	ENSPTRP00000028112	ENSPTRP00000051735	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	SHC (Src homology 2 domain containing) transforming protein 1.	0.570
EGF	SRC	ENSPTRP00000028112	ENSPTRP00000076797	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase.	0.755
EGFR	EGF	ENSPTRP00000069741	ENSPTRP00000028112	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	ERBB2	ENSPTRP00000069741	ENSPTRP00000069840	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.996
EGFR	ERBB3	ENSPTRP00000069741	ENSPTRP00000008639	Receptor protein-tyrosine kinase.	V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian).	0.992
EGFR	ERBB4	ENSPTRP00000069741	ENSPTRP00000063299	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.951
EGFR	GRB2	ENSPTRP00000069741	ENSPTRP00000016382	Receptor protein-tyrosine kinase.	Growth factor receptor-bound protein 2.	0.999
EGFR	NRG1	ENSPTRP00000069741	ENSPTRP00000092088	Receptor protein-tyrosine kinase.	NRG1 isoform 3.	0.994
EGFR	PIK3CA	ENSPTRP00000069741	ENSPTRP00000084763	Receptor protein-tyrosine kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.997
EGFR	PIK3R1	ENSPTRP00000069741	ENSPTRP00000076964	Receptor protein-tyrosine kinase.	Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha).	0.997
EGFR	SHC1	ENSPTRP00000069741	ENSPTRP00000051735	Receptor protein-tyrosine kinase.	SHC (Src homology 2 domain containing) transforming protein 1.	0.996
EGFR	SRC	ENSPTRP00000069741	ENSPTRP00000076797	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.997