| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD19 | CD79A | ENSPTRP00000079367 | ENSPTRP00000018954 | CD19 isoform 1. | CD79A isoform 1. | 0.991 |
| CD19 | CD81 | ENSPTRP00000079367 | ENSPTRP00000074537 | CD19 isoform 1. | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | 0.993 |
| CD19 | CR2 | ENSPTRP00000079367 | ENSPTRP00000003238 | CD19 isoform 1. | Complement C3d receptor 2. | 0.968 |
| CD19 | LYN | ENSPTRP00000079367 | ENSPTRP00000046608 | CD19 isoform 1. | Tyrosine-protein kinase. | 0.986 |
| CD19 | PIK3CA | ENSPTRP00000079367 | ENSPTRP00000084763 | CD19 isoform 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.963 |
| CD19 | PIK3CD | ENSPTRP00000079367 | ENSPTRP00000000229 | CD19 isoform 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.962 |
| CD19 | PIK3R1 | ENSPTRP00000079367 | ENSPTRP00000076964 | CD19 isoform 1. | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). | 0.982 |
| CD19 | VAV1 | ENSPTRP00000079367 | ENSPTRP00000017657 | CD19 isoform 1. | Vav guanine nucleotide exchange factor 1. | 0.998 |
| CD19 | VAV2 | ENSPTRP00000079367 | ENSPTRP00000084067 | CD19 isoform 1. | Vav guanine nucleotide exchange factor 2. | 0.983 |
| CD19 | VAV3 | ENSPTRP00000079367 | ENSPTRP00000090176 | CD19 isoform 1. | VAV3 isoform 2. | 0.983 |
| CD79A | CD19 | ENSPTRP00000018954 | ENSPTRP00000079367 | CD79A isoform 1. | CD19 isoform 1. | 0.991 |
| CD79A | CR2 | ENSPTRP00000018954 | ENSPTRP00000003238 | CD79A isoform 1. | Complement C3d receptor 2. | 0.588 |
| CD79A | LYN | ENSPTRP00000018954 | ENSPTRP00000046608 | CD79A isoform 1. | Tyrosine-protein kinase. | 0.987 |
| CD79A | VAV1 | ENSPTRP00000018954 | ENSPTRP00000017657 | CD79A isoform 1. | Vav guanine nucleotide exchange factor 1. | 0.659 |
| CD79A | VAV2 | ENSPTRP00000018954 | ENSPTRP00000084067 | CD79A isoform 1. | Vav guanine nucleotide exchange factor 2. | 0.567 |
| CD79A | VAV3 | ENSPTRP00000018954 | ENSPTRP00000090176 | CD79A isoform 1. | VAV3 isoform 2. | 0.544 |
| CD81 | CD19 | ENSPTRP00000074537 | ENSPTRP00000079367 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | CD19 isoform 1. | 0.993 |
| CD81 | CR2 | ENSPTRP00000074537 | ENSPTRP00000003238 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Complement C3d receptor 2. | 0.700 |
| CR2 | CD19 | ENSPTRP00000003238 | ENSPTRP00000079367 | Complement C3d receptor 2. | CD19 isoform 1. | 0.968 |
| CR2 | CD79A | ENSPTRP00000003238 | ENSPTRP00000018954 | Complement C3d receptor 2. | CD79A isoform 1. | 0.588 |
