USP10 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD44	USP10	ENSPTRP00000090688	ENSPTRP00000079859	ANKRD44 isoform 3.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.760
CAPRIN1	ENSPTRP00000083721	ENSPTRP00000006065	ENSPTRP00000083721	Cell cycle associated protein 1.	annotation not available	0.886
CAPRIN1	G3BP1	ENSPTRP00000006065	ENSPTRP00000077548	Cell cycle associated protein 1.	GTPase activating protein (SH3 domain) binding protein 1.	0.982
CAPRIN1	G3BP2	ENSPTRP00000006065	ENSPTRP00000040810	Cell cycle associated protein 1.	GTPase activating protein (SH3 domain) binding protein 2.	0.988
CAPRIN1	PABPC1	ENSPTRP00000006065	ENSPTRP00000069297	Cell cycle associated protein 1.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.452
CAPRIN1	USP10	ENSPTRP00000006065	ENSPTRP00000079859	Cell cycle associated protein 1.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.737
CFTR	UBC	ENSPTRP00000033597	ENSPTRP00000050925	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.450
CFTR	USP10	ENSPTRP00000033597	ENSPTRP00000079859	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.889
ENSPTRP00000083721	CAPRIN1	ENSPTRP00000083721	ENSPTRP00000006065	annotation not available	Cell cycle associated protein 1.	0.886
ENSPTRP00000083721	G3BP2	ENSPTRP00000083721	ENSPTRP00000040810	annotation not available	GTPase activating protein (SH3 domain) binding protein 2.	0.869
ENSPTRP00000083721	PABPC1	ENSPTRP00000083721	ENSPTRP00000069297	annotation not available	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.570
ENSPTRP00000083721	TP53	ENSPTRP00000083721	ENSPTRP00000014836	annotation not available	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.524
ENSPTRP00000083721	USP10	ENSPTRP00000083721	ENSPTRP00000079859	annotation not available	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.829
G3BP1	CAPRIN1	ENSPTRP00000077548	ENSPTRP00000006065	GTPase activating protein (SH3 domain) binding protein 1.	Cell cycle associated protein 1.	0.982
G3BP1	G3BP2	ENSPTRP00000077548	ENSPTRP00000040810	GTPase activating protein (SH3 domain) binding protein 1.	GTPase activating protein (SH3 domain) binding protein 2.	0.952
G3BP1	PABPC1	ENSPTRP00000077548	ENSPTRP00000069297	GTPase activating protein (SH3 domain) binding protein 1.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.917
G3BP1	TP53	ENSPTRP00000077548	ENSPTRP00000014836	GTPase activating protein (SH3 domain) binding protein 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.540
G3BP1	USP10	ENSPTRP00000077548	ENSPTRP00000079859	GTPase activating protein (SH3 domain) binding protein 1.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.913
G3BP2	CAPRIN1	ENSPTRP00000040810	ENSPTRP00000006065	GTPase activating protein (SH3 domain) binding protein 2.	Cell cycle associated protein 1.	0.988
G3BP2	ENSPTRP00000083721	ENSPTRP00000040810	ENSPTRP00000083721	GTPase activating protein (SH3 domain) binding protein 2.	annotation not available	0.869