node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKT1 | BAD | ENSPTRP00000082849 | ENSPTRP00000093875 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Bcl2-associated agonist of cell death. | 0.995 |
AKT1 | CDKN1A | ENSPTRP00000082849 | ENSPTRP00000060292 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | 0.995 |
AKT1 | CDKN1B | ENSPTRP00000082849 | ENSPTRP00000008044 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | 0.996 |
AKT1 | CHUK | ENSPTRP00000082849 | ENSPTRP00000084209 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Component of inhibitor of nuclear factor kappa B kinase complex. | 0.997 |
AKT1 | FOXO1 | ENSPTRP00000082849 | ENSPTRP00000009886 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | FOXO1 isoform 1. | 0.992 |
AKT1 | GSK3A | ENSPTRP00000082849 | ENSPTRP00000018979 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Glycogen synthase kinase 3 alpha. | 0.994 |
AKT1 | HSP90AA1 | ENSPTRP00000082849 | ENSPTRP00000070946 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.999 |
AKT1 | HSP90AB1 | ENSPTRP00000082849 | ENSPTRP00000031135 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | HSP90AB1 isoform 1. | 0.994 |
AKT1 | MTOR | ENSPTRP00000082849 | ENSPTRP00000000280 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. | 0.997 |
AKT1 | PHLPP1 | ENSPTRP00000082849 | ENSPTRP00000017119 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | PH domain and leucine rich repeat protein phosphatase 1. | 0.994 |
BAD | AKT1 | ENSPTRP00000093875 | ENSPTRP00000082849 | Bcl2-associated agonist of cell death. | AKT1 isoform 3; Belongs to the protein kinase superfamily. | 0.995 |
CDKN1A | AKT1 | ENSPTRP00000060292 | ENSPTRP00000082849 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | AKT1 isoform 3; Belongs to the protein kinase superfamily. | 0.995 |
CDKN1A | CDKN1B | ENSPTRP00000060292 | ENSPTRP00000008044 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | 0.994 |
CDKN1A | FOXO1 | ENSPTRP00000060292 | ENSPTRP00000009886 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | FOXO1 isoform 1. | 0.577 |
CDKN1A | HSP90AA1 | ENSPTRP00000060292 | ENSPTRP00000070946 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.700 |
CDKN1A | HSP90AB1 | ENSPTRP00000060292 | ENSPTRP00000031135 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | HSP90AB1 isoform 1. | 0.638 |
CDKN1B | AKT1 | ENSPTRP00000008044 | ENSPTRP00000082849 | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | AKT1 isoform 3; Belongs to the protein kinase superfamily. | 0.996 |
CDKN1B | CDKN1A | ENSPTRP00000008044 | ENSPTRP00000060292 | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | 0.994 |
CDKN1B | FOXO1 | ENSPTRP00000008044 | ENSPTRP00000009886 | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | FOXO1 isoform 1. | 0.592 |
CDKN1B | GSK3A | ENSPTRP00000008044 | ENSPTRP00000018979 | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | Glycogen synthase kinase 3 alpha. | 0.473 |