| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CK820_G0020029 | EIF4A1 | ENSPTRP00000083028 | ENSPTRP00000014825 | PABPC1L isoform 9. | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | 0.668 |
| CK820_G0020029 | EIF4A2 | ENSPTRP00000083028 | ENSPTRP00000027042 | PABPC1L isoform 9. | Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. | 0.668 |
| CK820_G0020029 | EIF4E | ENSPTRP00000083028 | ENSPTRP00000069083 | PABPC1L isoform 9. | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | 0.714 |
| CK820_G0020029 | EIF4E1B | ENSPTRP00000083028 | ENSPTRP00000047824 | PABPC1L isoform 9. | Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. | 0.680 |
| CK820_G0020029 | EIF4G1 | ENSPTRP00000083028 | ENSPTRP00000026995 | PABPC1L isoform 9. | Eukaryotic translation initiation factor 4 gamma 1. | 0.800 |
| CK820_G0020029 | ENSPTRP00000091185 | ENSPTRP00000083028 | ENSPTRP00000091185 | PABPC1L isoform 9. | annotation not available | 0.699 |
| CK820_G0020029 | NCBP2 | ENSPTRP00000083028 | ENSPTRP00000080568 | PABPC1L isoform 9. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.669 |
| CK820_G0020029 | PAIP1 | ENSPTRP00000083028 | ENSPTRP00000048224 | PABPC1L isoform 9. | Poly(A) binding protein interacting protein 1. | 0.674 |
| CK820_G0020029 | PAN2 | ENSPTRP00000083028 | ENSPTRP00000074921 | PABPC1L isoform 9. | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] | 0.705 |
| CK820_G0020029 | PAN3 | ENSPTRP00000083028 | ENSPTRP00000053597 | PABPC1L isoform 9. | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] | 0.705 |
| EIF4A1 | CK820_G0020029 | ENSPTRP00000014825 | ENSPTRP00000083028 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | PABPC1L isoform 9. | 0.668 |
| EIF4A1 | EIF4A2 | ENSPTRP00000014825 | ENSPTRP00000027042 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. | 0.998 |
| EIF4A1 | EIF4E | ENSPTRP00000014825 | ENSPTRP00000069083 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | 0.992 |
| EIF4A1 | EIF4E1B | ENSPTRP00000014825 | ENSPTRP00000047824 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. | 0.577 |
| EIF4A1 | EIF4G1 | ENSPTRP00000014825 | ENSPTRP00000026995 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | Eukaryotic translation initiation factor 4 gamma 1. | 0.999 |
| EIF4A1 | NCBP2 | ENSPTRP00000014825 | ENSPTRP00000080568 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.509 |
| EIF4A1 | PAIP1 | ENSPTRP00000014825 | ENSPTRP00000048224 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | Poly(A) binding protein interacting protein 1. | 0.985 |
| EIF4A1 | PAN2 | ENSPTRP00000014825 | ENSPTRP00000074921 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] | 0.409 |
| EIF4A2 | CK820_G0020029 | ENSPTRP00000027042 | ENSPTRP00000083028 | Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. | PABPC1L isoform 9. | 0.668 |
| EIF4A2 | EIF4A1 | ENSPTRP00000027042 | ENSPTRP00000014825 | Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | 0.998 |