| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | DHODH | ENSPTRP00000083069 | ENSPTRP00000014234 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.552 |
| ALDH18A1 | DPYD | ENSPTRP00000083069 | ENSPTRP00000001697 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.715 |
| ALDH18A1 | FADS6 | ENSPTRP00000083069 | ENSPTRP00000083029 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Fatty acid desaturase 6. | 0.810 |
| ALDH18A1 | GMPS | ENSPTRP00000083069 | ENSPTRP00000026780 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Guanine monphosphate synthetase. | 0.922 |
| ALDH18A1 | NDUFV1 | ENSPTRP00000083069 | ENSPTRP00000006828 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.924 |
| ALDH18A1 | TMEM109 | ENSPTRP00000083069 | ENSPTRP00000006407 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Transmembrane protein 109. | 0.473 |
| DHODH | ALDH18A1 | ENSPTRP00000014234 | ENSPTRP00000083069 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.552 |
| DHODH | DPYD | ENSPTRP00000014234 | ENSPTRP00000001697 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.405 |
| DHODH | FADS6 | ENSPTRP00000014234 | ENSPTRP00000083029 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Fatty acid desaturase 6. | 0.717 |
| DHODH | GMPS | ENSPTRP00000014234 | ENSPTRP00000026780 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Guanine monphosphate synthetase. | 0.848 |
| DPYD | ALDH18A1 | ENSPTRP00000001697 | ENSPTRP00000083069 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.715 |
| DPYD | DHODH | ENSPTRP00000001697 | ENSPTRP00000014234 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.405 |
| DPYD | FADS6 | ENSPTRP00000001697 | ENSPTRP00000083029 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Fatty acid desaturase 6. | 0.717 |
| DPYD | GMPS | ENSPTRP00000001697 | ENSPTRP00000026780 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Guanine monphosphate synthetase. | 0.783 |
| ENSPTRP00000066774 | FADS6 | ENSPTRP00000066774 | ENSPTRP00000083029 | annotation not available | Fatty acid desaturase 6. | 0.806 |
| ENSPTRP00000066774 | FDX2 | ENSPTRP00000066774 | ENSPTRP00000017830 | annotation not available | T0092363 isoform 1. | 0.638 |
| ENSPTRP00000066774 | NDUFV1 | ENSPTRP00000066774 | ENSPTRP00000006828 | annotation not available | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.675 |
| FADS6 | ALDH18A1 | ENSPTRP00000083029 | ENSPTRP00000083069 | Fatty acid desaturase 6. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.810 |
| FADS6 | DHODH | ENSPTRP00000083029 | ENSPTRP00000014234 | Fatty acid desaturase 6. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.717 |
| FADS6 | DPYD | ENSPTRP00000083029 | ENSPTRP00000001697 | Fatty acid desaturase 6. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.717 |
