Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PRSS1Serine protease 1; Belongs to the peptidase S1 family. (261 aa)    
Predicted Functional Partners:
SPINK1
Serine peptidase inhibitor, Kazal type 1.
   
 0.858
COLEC11
Collectin subfamily member 11.
    
 0.810
F2RL3
F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.762
F2RL2
Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.723
CTRB2
Chymotrypsinogen B2.
  
0.722
CPA1
CPA1 isoform 2.
   
 
 0.714
F2RL1
F2R like trypsin receptor 1.
    
 0.710
F2R
Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.708
LOC736783
Chymotrypsinogen B2.
  
 
0.673
SPINT2
T0106202 isoform 2.
    
 0.665
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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