OXCT1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AACS	ACAT1	ENSPTRP00000009564	ENSPTRP00000007309	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.945
AACS	ACAT2	ENSPTRP00000009564	ENSPTRP00000032016	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.941
AACS	BDH1	ENSPTRP00000009564	ENSPTRP00000075393	Acetoacetyl-CoA synthetase.	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.919
AACS	EHHADH	ENSPTRP00000009564	ENSPTRP00000027013	Acetoacetyl-CoA synthetase.	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.928
AACS	HADH	ENSPTRP00000009564	ENSPTRP00000062385	Acetoacetyl-CoA synthetase.	Hydroxyacyl-CoA dehydrogenase.	0.939
AACS	HMGCL	ENSPTRP00000009564	ENSPTRP00000000589	Acetoacetyl-CoA synthetase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase.	0.934
AACS	HMGCLL1	ENSPTRP00000009564	ENSPTRP00000055570	Acetoacetyl-CoA synthetase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.934
AACS	HMGCS1	ENSPTRP00000009564	ENSPTRP00000028865	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.935
AACS	HMGCS2	ENSPTRP00000009564	ENSPTRP00000002014	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.939
AACS	OXCT1	ENSPTRP00000009564	ENSPTRP00000084492	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.930
ACAT1	AACS	ENSPTRP00000007309	ENSPTRP00000009564	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetyl-CoA synthetase.	0.945
ACAT1	ACAT2	ENSPTRP00000007309	ENSPTRP00000032016	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.932
ACAT1	BDH1	ENSPTRP00000007309	ENSPTRP00000075393	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.602
ACAT1	EHHADH	ENSPTRP00000007309	ENSPTRP00000027013	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.968
ACAT1	HADH	ENSPTRP00000007309	ENSPTRP00000062385	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxyacyl-CoA dehydrogenase.	0.992
ACAT1	HMGCL	ENSPTRP00000007309	ENSPTRP00000000589	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxymethyl-3-methylglutaryl-CoA lyase.	0.946
ACAT1	HMGCLL1	ENSPTRP00000007309	ENSPTRP00000055570	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.940
ACAT1	HMGCS1	ENSPTRP00000007309	ENSPTRP00000028865	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.989
ACAT1	HMGCS2	ENSPTRP00000007309	ENSPTRP00000002014	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.990
ACAT1	OXCT1	ENSPTRP00000007309	ENSPTRP00000084492	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.976