STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3F3BH3 histone family member 3B. (136 aa)    
Predicted Functional Partners:
KDM1B
KDM1B isoform 4.
    
 0.936
GLYR1
Glyoxylate reductase 1 homolog.
    
 
 0.917
ATRX
Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...]
    
 0.915
H3C13
HIST2H3A isoform 1.
  
0.906
LOC746430
Uncharacterized LOC746430.
  
0.906
LOC107966300
Histone H3.
  
0.906
DAXX
Death domain associated protein.
    
 0.894
H3-4
HIST3H3 isoform 1.
  
 
 
0.889
LOC112209457-4
Histone H3.1.
  
 
 
0.888
LOC471875
Histone H3.1-like.
  
 
 
0.888
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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