| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD163 | CD68 | ENSPTRP00000086009 | ENSPTRP00000014826 | CD163 isoform 1. | CD68 isoform 1. | 0.805 |
| CD163 | CK820_G0040173 | ENSPTRP00000086009 | ENSPTRP00000055139 | CD163 isoform 1. | HP isoform 11. | 0.870 |
| CD163 | CSF1R | ENSPTRP00000086009 | ENSPTRP00000080883 | CD163 isoform 1. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.828 |
| CD163 | HBA2 | ENSPTRP00000086009 | ENSPTRP00000090491 | CD163 isoform 1. | Pan troglodytes hemoglobin subunit alpha 2 (HBA2), mRNA. | 0.792 |
| CD163 | HBB | ENSPTRP00000086009 | ENSPTRP00000005700 | CD163 isoform 1. | Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. | 0.793 |
| CD163 | HP | ENSPTRP00000086009 | ENSPTRP00000067098 | CD163 isoform 1. | HP isoform 15. | 0.904 |
| CD163 | HPR | ENSPTRP00000086009 | ENSPTRP00000062259 | CD163 isoform 1. | Haptoglobin-related protein; Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron. | 0.775 |
| CD163 | IL10 | ENSPTRP00000086009 | ENSPTRP00000003208 | CD163 isoform 1. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.778 |
| CD163 | MYH9 | ENSPTRP00000086009 | ENSPTRP00000078901 | CD163 isoform 1. | Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.872 |
| CD163 | VSIG4 | ENSPTRP00000086009 | ENSPTRP00000037758 | CD163 isoform 1. | V-set and immunoglobulin domain containing 4. | 0.913 |
| CD68 | CD163 | ENSPTRP00000014826 | ENSPTRP00000086009 | CD68 isoform 1. | CD163 isoform 1. | 0.805 |
| CD68 | CSF1R | ENSPTRP00000014826 | ENSPTRP00000080883 | CD68 isoform 1. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.797 |
| CD68 | IL10 | ENSPTRP00000014826 | ENSPTRP00000003208 | CD68 isoform 1. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.801 |
| CK820_G0040173 | CD163 | ENSPTRP00000055139 | ENSPTRP00000086009 | HP isoform 11. | CD163 isoform 1. | 0.870 |
| CK820_G0040173 | HBA2 | ENSPTRP00000055139 | ENSPTRP00000090491 | HP isoform 11. | Pan troglodytes hemoglobin subunit alpha 2 (HBA2), mRNA. | 0.819 |
| CK820_G0040173 | HBB | ENSPTRP00000055139 | ENSPTRP00000005700 | HP isoform 11. | Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. | 0.818 |
| CK820_G0040173 | HPR | ENSPTRP00000055139 | ENSPTRP00000062259 | HP isoform 11. | Haptoglobin-related protein; Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron. | 0.920 |
| CSF1R | CD163 | ENSPTRP00000080883 | ENSPTRP00000086009 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | CD163 isoform 1. | 0.828 |
| CSF1R | CD68 | ENSPTRP00000080883 | ENSPTRP00000014826 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | CD68 isoform 1. | 0.797 |
| CSF1R | IL10 | ENSPTRP00000080883 | ENSPTRP00000003208 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.438 |
