FOXP4-2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FOXP4-2

Forkhead box P4. (668 aa)

Predicted Functional Partners:

FOXP2

0.897

FOXP3

0.720

HAND1

0.649

SRPX2

0.612

FOXP1

0.605

CTBP1

0.599

HAND2

0.503

CBFB

0.495

NFATC2

0.487

CTBP2

0.465

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFB	FOXP1	ENSPTRP00000060319	ENSPTRP00000075187	Core-binding factor, beta subunit.	FOXP1 isoform 2.	0.572
CBFB	FOXP2	ENSPTRP00000060319	ENSPTRP00000071606	Core-binding factor, beta subunit.	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	0.557
CBFB	FOXP3	ENSPTRP00000060319	ENSPTRP00000037587	Core-binding factor, beta subunit.	FOXP3 isoform 4.	0.804
CBFB	FOXP4-2	ENSPTRP00000060319	ENSPTRP00000086765	Core-binding factor, beta subunit.	Forkhead box P4.	0.495
CTBP1	CTBP2	ENSPTRP00000077481	ENSPTRP00000005353	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	CTBP2 isoform 10.	0.994
CTBP1	FOXP1	ENSPTRP00000077481	ENSPTRP00000075187	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	FOXP1 isoform 2.	0.439
CTBP1	FOXP2	ENSPTRP00000077481	ENSPTRP00000071606	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	0.805
CTBP1	FOXP4-2	ENSPTRP00000077481	ENSPTRP00000086765	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Forkhead box P4.	0.599
CTBP2	CTBP1	ENSPTRP00000005353	ENSPTRP00000077481	CTBP2 isoform 10.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.994
CTBP2	FOXP1	ENSPTRP00000005353	ENSPTRP00000075187	CTBP2 isoform 10.	FOXP1 isoform 2.	0.410
CTBP2	FOXP4-2	ENSPTRP00000005353	ENSPTRP00000086765	CTBP2 isoform 10.	Forkhead box P4.	0.465
FOXP1	CBFB	ENSPTRP00000075187	ENSPTRP00000060319	FOXP1 isoform 2.	Core-binding factor, beta subunit.	0.572
FOXP1	CTBP1	ENSPTRP00000075187	ENSPTRP00000077481	FOXP1 isoform 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.439
FOXP1	CTBP2	ENSPTRP00000075187	ENSPTRP00000005353	FOXP1 isoform 2.	CTBP2 isoform 10.	0.410
FOXP1	FOXP2	ENSPTRP00000075187	ENSPTRP00000071606	FOXP1 isoform 2.	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	0.785
FOXP1	FOXP3	ENSPTRP00000075187	ENSPTRP00000037587	FOXP1 isoform 2.	FOXP3 isoform 4.	0.653
FOXP1	FOXP4-2	ENSPTRP00000075187	ENSPTRP00000086765	FOXP1 isoform 2.	Forkhead box P4.	0.605
FOXP1	NFATC2	ENSPTRP00000075187	ENSPTRP00000047128	FOXP1 isoform 2.	NFATC2 isoform 4.	0.643
FOXP1	SRPX2	ENSPTRP00000075187	ENSPTRP00000080928	FOXP1 isoform 2.	Sushi-repeat containing protein, X-linked 2.	0.552
FOXP2	CBFB	ENSPTRP00000071606	ENSPTRP00000060319	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	Core-binding factor, beta subunit.	0.557