| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSS1 | ADSS2 | ENSPTRP00000011563 | ENSPTRP00000003684 | Adenylosuccinate synthetase isozyme 1 isoform X2. | ADSS isoform 1. | 0.901 |
| ADSS1 | AMPD1 | ENSPTRP00000011563 | ENSPTRP00000074005 | Adenylosuccinate synthetase isozyme 1 isoform X2. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.942 |
| ADSS1 | AMPD2 | ENSPTRP00000011563 | ENSPTRP00000077089 | Adenylosuccinate synthetase isozyme 1 isoform X2. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.931 |
| ADSS1 | AMPD3 | ENSPTRP00000011563 | ENSPTRP00000005861 | Adenylosuccinate synthetase isozyme 1 isoform X2. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.931 |
| ADSS1 | HPRT1 | ENSPTRP00000011563 | ENSPTRP00000086770 | Adenylosuccinate synthetase isozyme 1 isoform X2. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.936 |
| ADSS1 | IMPDH2 | ENSPTRP00000011563 | ENSPTRP00000041919 | Adenylosuccinate synthetase isozyme 1 isoform X2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.948 |
| ADSS2 | ADSS1 | ENSPTRP00000003684 | ENSPTRP00000011563 | ADSS isoform 1. | Adenylosuccinate synthetase isozyme 1 isoform X2. | 0.901 |
| ADSS2 | AMPD1 | ENSPTRP00000003684 | ENSPTRP00000074005 | ADSS isoform 1. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.942 |
| ADSS2 | AMPD2 | ENSPTRP00000003684 | ENSPTRP00000077089 | ADSS isoform 1. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.931 |
| ADSS2 | AMPD3 | ENSPTRP00000003684 | ENSPTRP00000005861 | ADSS isoform 1. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.931 |
| ADSS2 | HPRT1 | ENSPTRP00000003684 | ENSPTRP00000086770 | ADSS isoform 1. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.936 |
| ADSS2 | IMPDH2 | ENSPTRP00000003684 | ENSPTRP00000041919 | ADSS isoform 1. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.981 |
| AMPD1 | ADSS1 | ENSPTRP00000074005 | ENSPTRP00000011563 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Adenylosuccinate synthetase isozyme 1 isoform X2. | 0.942 |
| AMPD1 | ADSS2 | ENSPTRP00000074005 | ENSPTRP00000003684 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | ADSS isoform 1. | 0.942 |
| AMPD1 | AMPD2 | ENSPTRP00000074005 | ENSPTRP00000077089 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.976 |
| AMPD1 | AMPD3 | ENSPTRP00000074005 | ENSPTRP00000005861 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.977 |
| AMPD1 | HPRT1 | ENSPTRP00000074005 | ENSPTRP00000086770 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.954 |
| AMPD1 | IMPDH2 | ENSPTRP00000074005 | ENSPTRP00000041919 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.940 |
| AMPD1 | PNP | ENSPTRP00000074005 | ENSPTRP00000010346 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.609 |
| AMPD2 | ADSS1 | ENSPTRP00000077089 | ENSPTRP00000011563 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Adenylosuccinate synthetase isozyme 1 isoform X2. | 0.931 |
