| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUL1 | CUL1-2 | ENSPTRP00000033967 | ENSPTRP00000086353 | CUL1 isoform 1; Belongs to the cullin family. | Cullin 1. | 0.801 |
| CUL1 | CUL3 | ENSPTRP00000033967 | ENSPTRP00000022190 | CUL1 isoform 1; Belongs to the cullin family. | CUL3 isoform 2; Belongs to the cullin family. | 0.795 |
| CUL1 | CUL5 | ENSPTRP00000033967 | ENSPTRP00000007307 | CUL1 isoform 1; Belongs to the cullin family. | CUL5 isoform 1; Belongs to the cullin family. | 0.459 |
| CUL1 | ENSPTRP00000084393 | ENSPTRP00000033967 | ENSPTRP00000084393 | CUL1 isoform 1; Belongs to the cullin family. | annotation not available | 0.844 |
| CUL1 | NAE1 | ENSPTRP00000033967 | ENSPTRP00000091978 | CUL1 isoform 1; Belongs to the cullin family. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.761 |
| CUL1 | NEDD8 | ENSPTRP00000033967 | ENSPTRP00000090523 | CUL1 isoform 1; Belongs to the cullin family. | Ubiquitin-like protein Nedd8. | 0.886 |
| CUL1 | RBX1 | ENSPTRP00000033967 | ENSPTRP00000024839 | CUL1 isoform 1; Belongs to the cullin family. | Ring-box 1, E3 ubiquitin protein ligase. | 0.997 |
| CUL1 | RNF7 | ENSPTRP00000033967 | ENSPTRP00000071278 | CUL1 isoform 1; Belongs to the cullin family. | Ring finger protein 7. | 0.866 |
| CUL1 | UBA3 | ENSPTRP00000033967 | ENSPTRP00000043591 | CUL1 isoform 1; Belongs to the cullin family. | Ubiquitin-like modifier-activating enzyme 3. | 0.813 |
| CUL1 | UBE2F | ENSPTRP00000033967 | ENSPTRP00000087042 | CUL1 isoform 1; Belongs to the cullin family. | Ubiquitin conjugating enzyme E2 F (putative); Belongs to the ubiquitin-conjugating enzyme family. | 0.775 |
| CUL1-2 | CUL1 | ENSPTRP00000086353 | ENSPTRP00000033967 | Cullin 1. | CUL1 isoform 1; Belongs to the cullin family. | 0.801 |
| CUL1-2 | CUL3 | ENSPTRP00000086353 | ENSPTRP00000022190 | Cullin 1. | CUL3 isoform 2; Belongs to the cullin family. | 0.795 |
| CUL1-2 | CUL5 | ENSPTRP00000086353 | ENSPTRP00000007307 | Cullin 1. | CUL5 isoform 1; Belongs to the cullin family. | 0.459 |
| CUL1-2 | ENSPTRP00000084393 | ENSPTRP00000086353 | ENSPTRP00000084393 | Cullin 1. | annotation not available | 0.844 |
| CUL1-2 | NAE1 | ENSPTRP00000086353 | ENSPTRP00000091978 | Cullin 1. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.761 |
| CUL1-2 | NEDD8 | ENSPTRP00000086353 | ENSPTRP00000090523 | Cullin 1. | Ubiquitin-like protein Nedd8. | 0.886 |
| CUL1-2 | RBX1 | ENSPTRP00000086353 | ENSPTRP00000024839 | Cullin 1. | Ring-box 1, E3 ubiquitin protein ligase. | 0.974 |
| CUL1-2 | RNF7 | ENSPTRP00000086353 | ENSPTRP00000071278 | Cullin 1. | Ring finger protein 7. | 0.866 |
| CUL1-2 | UBA3 | ENSPTRP00000086353 | ENSPTRP00000043591 | Cullin 1. | Ubiquitin-like modifier-activating enzyme 3. | 0.813 |
| CUL1-2 | UBE2F | ENSPTRP00000086353 | ENSPTRP00000087042 | Cullin 1. | Ubiquitin conjugating enzyme E2 F (putative); Belongs to the ubiquitin-conjugating enzyme family. | 0.775 |
