| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CLSPN | MYC | ENSPTRP00000047143 | ENSPTRP00000075568 | CLSPN isoform 1. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | 0.591 |
| CLSPN | USP28 | ENSPTRP00000047143 | ENSPTRP00000088705 | CLSPN isoform 1. | USP28 isoform 2; Belongs to the peptidase C19 family. | 0.882 |
| ENSPTRP00000060412 | KXD1 | ENSPTRP00000060412 | ENSPTRP00000060271 | annotation not available | UBA52 isoform 10. | 0.999 |
| ENSPTRP00000060412 | MYC | ENSPTRP00000060412 | ENSPTRP00000075568 | annotation not available | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | 0.824 |
| ENSPTRP00000060412 | RPS27A | ENSPTRP00000060412 | ENSPTRP00000020489 | annotation not available | RPS27A isoform 1. | 0.900 |
| ENSPTRP00000060412 | TP53 | ENSPTRP00000060412 | ENSPTRP00000014836 | annotation not available | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.963 |
| ENSPTRP00000060412 | TP53BP1 | ENSPTRP00000060412 | ENSPTRP00000067532 | annotation not available | Tumor protein p53 binding protein 1. | 0.848 |
| ENSPTRP00000060412 | TRIP12 | ENSPTRP00000060412 | ENSPTRP00000091338 | annotation not available | Thyroid hormone receptor interactor 12. | 0.896 |
| ENSPTRP00000060412 | UBC | ENSPTRP00000060412 | ENSPTRP00000050925 | annotation not available | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.998 |
| ENSPTRP00000060412 | USP28 | ENSPTRP00000060412 | ENSPTRP00000088705 | annotation not available | USP28 isoform 2; Belongs to the peptidase C19 family. | 0.779 |
| KXD1 | ENSPTRP00000060412 | ENSPTRP00000060271 | ENSPTRP00000060412 | UBA52 isoform 10. | annotation not available | 0.999 |
| KXD1 | RPS27A | ENSPTRP00000060271 | ENSPTRP00000020489 | UBA52 isoform 10. | RPS27A isoform 1. | 0.999 |
| KXD1 | TP53 | ENSPTRP00000060271 | ENSPTRP00000014836 | UBA52 isoform 10. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.512 |
| KXD1 | TP53BP1 | ENSPTRP00000060271 | ENSPTRP00000067532 | UBA52 isoform 10. | Tumor protein p53 binding protein 1. | 0.798 |
| KXD1 | TRIP12 | ENSPTRP00000060271 | ENSPTRP00000091338 | UBA52 isoform 10. | Thyroid hormone receptor interactor 12. | 0.908 |
| KXD1 | UBC | ENSPTRP00000060271 | ENSPTRP00000050925 | UBA52 isoform 10. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.999 |
| KXD1 | USP28 | ENSPTRP00000060271 | ENSPTRP00000088705 | UBA52 isoform 10. | USP28 isoform 2; Belongs to the peptidase C19 family. | 0.779 |
| MYC | CLSPN | ENSPTRP00000075568 | ENSPTRP00000047143 | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | CLSPN isoform 1. | 0.591 |
| MYC | ENSPTRP00000060412 | ENSPTRP00000075568 | ENSPTRP00000060412 | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | annotation not available | 0.824 |
| MYC | RPS27A | ENSPTRP00000075568 | ENSPTRP00000020489 | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | RPS27A isoform 1. | 0.770 |
