Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HLA-APatr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system. (365 aa)    
Predicted Functional Partners:
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
   
 0.988
KIR2DL6-2
KIR2DL4 isoform 7.
    
 0.980
TAPBP
TAP binding protein.
   
 0.970
CALR
Calreticulin.
    
 0.962
KLRD1
Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
    
 0.951
PDIA3
Protein disulfide-isomerase.
    
 0.947
BV7-9
TRBV7-9 isoform 1.
  
 
  0.936
CD8B
CD8B isoform 3.
     
 0.931
KIR3DL5
Pan troglodytes killer cell immunoglobulin-like receptor (KIR3DL5), mRNA.
    
 0.913
TAPBPL
TAPBPL isoform 3.
   
 
  0.901
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (46%) [HD]