SF1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX17	DDX5	ENSPTRP00000062822	ENSPTRP00000016210	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	0.995
DDX17	PRPF40A	ENSPTRP00000062822	ENSPTRP00000040608	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	PRP40 pre-mRNA processing factor 40 homolog A.	0.722
DDX17	RBM25	ENSPTRP00000062822	ENSPTRP00000011043	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	RNA binding motif protein 25.	0.839
DDX17	SF1	ENSPTRP00000062822	ENSPTRP00000089629	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Splicing factor 1.	0.927
DDX17	SF3A2	ENSPTRP00000062822	ENSPTRP00000017387	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Splicing factor 3a, subunit 2, 66kDa.	0.713
DDX17	SF3B1	ENSPTRP00000062822	ENSPTRP00000021823	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Splicing factor 3b, subunit 1, 155kDa.	0.762
DDX17	SUGP1	ENSPTRP00000062822	ENSPTRP00000018317	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	SURP and G-patch domain containing 1.	0.634
DDX17	U2AF2	ENSPTRP00000062822	ENSPTRP00000091126	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.745
DDX46	PRPF40A	ENSPTRP00000081460	ENSPTRP00000040608	DEAD-box helicase 46.	PRP40 pre-mRNA processing factor 40 homolog A.	0.945
DDX46	RBM25	ENSPTRP00000081460	ENSPTRP00000011043	DEAD-box helicase 46.	RNA binding motif protein 25.	0.936
DDX46	SF1	ENSPTRP00000081460	ENSPTRP00000089629	DEAD-box helicase 46.	Splicing factor 1.	0.889
DDX46	SF3A1	ENSPTRP00000081460	ENSPTRP00000049734	DEAD-box helicase 46.	Splicing factor 3a, subunit 1, 120kDa.	0.944
DDX46	SF3A2	ENSPTRP00000081460	ENSPTRP00000017387	DEAD-box helicase 46.	Splicing factor 3a, subunit 2, 66kDa.	0.979
DDX46	SF3B1	ENSPTRP00000081460	ENSPTRP00000021823	DEAD-box helicase 46.	Splicing factor 3b, subunit 1, 155kDa.	0.977
DDX46	U2AF2	ENSPTRP00000081460	ENSPTRP00000091126	DEAD-box helicase 46.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.847
DDX5	DDX17	ENSPTRP00000016210	ENSPTRP00000062822	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.995
DDX5	PRPF40A	ENSPTRP00000016210	ENSPTRP00000040608	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	PRP40 pre-mRNA processing factor 40 homolog A.	0.875
DDX5	RBM25	ENSPTRP00000016210	ENSPTRP00000011043	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	RNA binding motif protein 25.	0.874
DDX5	SF1	ENSPTRP00000016210	ENSPTRP00000089629	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	Splicing factor 1.	0.923
DDX5	SF3A1	ENSPTRP00000016210	ENSPTRP00000049734	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	Splicing factor 3a, subunit 1, 120kDa.	0.455