| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FOXO3 | MAPK1 | ENSPTRP00000049754 | ENSPTRP00000024313 | FOXO3 isoform 1. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.942 |
| FOXO3 | SMAD2 | ENSPTRP00000049754 | ENSPTRP00000062376 | FOXO3 isoform 1. | Mothers against decapentaplegic homolog. | 0.967 |
| FOXO3 | SMAD3 | ENSPTRP00000049754 | ENSPTRP00000090625 | FOXO3 isoform 1. | Mothers against decapentaplegic homolog. | 0.985 |
| FOXO3 | SMAD4 | ENSPTRP00000049754 | ENSPTRP00000017047 | FOXO3 isoform 1. | Mothers against decapentaplegic homolog. | 0.820 |
| FOXO3 | SMAD9 | ENSPTRP00000049754 | ENSPTRP00000057678 | FOXO3 isoform 1. | Mothers against decapentaplegic homolog. | 0.477 |
| LEMD3 | SMAD2 | ENSPTRP00000008804 | ENSPTRP00000062376 | LEM domain containing 3. | Mothers against decapentaplegic homolog. | 0.974 |
| LEMD3 | SMAD3 | ENSPTRP00000008804 | ENSPTRP00000090625 | LEM domain containing 3. | Mothers against decapentaplegic homolog. | 0.984 |
| LEMD3 | SMAD9 | ENSPTRP00000008804 | ENSPTRP00000057678 | LEM domain containing 3. | Mothers against decapentaplegic homolog. | 0.827 |
| MAPK1 | FOXO3 | ENSPTRP00000024313 | ENSPTRP00000049754 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | FOXO3 isoform 1. | 0.942 |
| MAPK1 | SMAD2 | ENSPTRP00000024313 | ENSPTRP00000062376 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mothers against decapentaplegic homolog. | 0.975 |
| MAPK1 | SMAD3 | ENSPTRP00000024313 | ENSPTRP00000090625 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mothers against decapentaplegic homolog. | 0.984 |
| MAPK1 | SMAD4 | ENSPTRP00000024313 | ENSPTRP00000017047 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mothers against decapentaplegic homolog. | 0.647 |
| MAPK1 | SMAD9 | ENSPTRP00000024313 | ENSPTRP00000057678 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mothers against decapentaplegic homolog. | 0.520 |
| SMAD2 | FOXO3 | ENSPTRP00000062376 | ENSPTRP00000049754 | Mothers against decapentaplegic homolog. | FOXO3 isoform 1. | 0.967 |
| SMAD2 | LEMD3 | ENSPTRP00000062376 | ENSPTRP00000008804 | Mothers against decapentaplegic homolog. | LEM domain containing 3. | 0.974 |
| SMAD2 | MAPK1 | ENSPTRP00000062376 | ENSPTRP00000024313 | Mothers against decapentaplegic homolog. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.975 |
| SMAD2 | SMAD3 | ENSPTRP00000062376 | ENSPTRP00000090625 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD2 | SMAD4 | ENSPTRP00000062376 | ENSPTRP00000017047 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD2 | SMAD7 | ENSPTRP00000062376 | ENSPTRP00000017016 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.991 |
| SMAD2 | SMAD9 | ENSPTRP00000062376 | ENSPTRP00000057678 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.970 |
