STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IZUMO4IZUMO family member 4. (232 aa)    
Predicted Functional Partners:
IZUMO2
IZUMO family member 2.
      
 0.843
ZPBP
Zona pellucida binding protein.
   
  
 0.840
DMRTC2
DMRT like family C2.
      
 0.832
WDR48
WD repeat domain 48.
      
 0.821
IZUMO3
IZUMO family member 3.
      
 0.811
SIAH1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
      
 0.776
PLPP1
Phospholipid phosphatase 1.
      
 0.740
ADAM32
ADAM metallopeptidase domain 32.
   
  
 0.737
BAZ1B
Bromodomain adjacent to zinc finger domain, 1B.
   
  
 0.733
CD9
Tetraspanin.
     
 0.722
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.