node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACKR1 | BTLA | ENSPTRP00000002561 | ENSPTRP00000040260 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | B and T lymphocyte associated. | 0.594 |
ACKR1 | CD160 | ENSPTRP00000002561 | ENSPTRP00000081465 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | CD160 isoform 5. | 0.544 |
ACKR1 | LTBR | ENSPTRP00000002561 | ENSPTRP00000007817 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.459 |
ACKR1 | TNFRSF14 | ENSPTRP00000002561 | ENSPTRP00000000096 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Tumor necrosis factor receptor superfamily, member 14 (Herpesvirus entry mediator). | 0.906 |
ACKR1 | TNFSF14 | ENSPTRP00000002561 | ENSPTRP00000093736 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. | 0.674 |
BTLA | ACKR1 | ENSPTRP00000040260 | ENSPTRP00000002561 | B and T lymphocyte associated. | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | 0.594 |
BTLA | CD160 | ENSPTRP00000040260 | ENSPTRP00000081465 | B and T lymphocyte associated. | CD160 isoform 5. | 0.863 |
BTLA | CD40 | ENSPTRP00000040260 | ENSPTRP00000068307 | B and T lymphocyte associated. | CD40 molecule, TNF receptor superfamily member 5. | 0.732 |
BTLA | LTA | ENSPTRP00000040260 | ENSPTRP00000030651 | B and T lymphocyte associated. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | 0.407 |
BTLA | LTBR | ENSPTRP00000040260 | ENSPTRP00000007817 | B and T lymphocyte associated. | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.660 |
BTLA | TNFRSF11B | ENSPTRP00000040260 | ENSPTRP00000035110 | B and T lymphocyte associated. | Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. | 0.616 |
BTLA | TNFRSF14 | ENSPTRP00000040260 | ENSPTRP00000000096 | B and T lymphocyte associated. | Tumor necrosis factor receptor superfamily, member 14 (Herpesvirus entry mediator). | 0.998 |
BTLA | TNFRSF18 | ENSPTRP00000040260 | ENSPTRP00000089804 | B and T lymphocyte associated. | TNFRSF18 isoform 1. | 0.755 |
BTLA | TNFSF14 | ENSPTRP00000040260 | ENSPTRP00000093736 | B and T lymphocyte associated. | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. | 0.673 |
CD160 | ACKR1 | ENSPTRP00000081465 | ENSPTRP00000002561 | CD160 isoform 5. | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | 0.544 |
CD160 | BTLA | ENSPTRP00000081465 | ENSPTRP00000040260 | CD160 isoform 5. | B and T lymphocyte associated. | 0.863 |
CD160 | TNFRSF14 | ENSPTRP00000081465 | ENSPTRP00000000096 | CD160 isoform 5. | Tumor necrosis factor receptor superfamily, member 14 (Herpesvirus entry mediator). | 0.909 |
CD160 | TNFSF14 | ENSPTRP00000081465 | ENSPTRP00000093736 | CD160 isoform 5. | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. | 0.932 |
CD40 | BTLA | ENSPTRP00000068307 | ENSPTRP00000040260 | CD40 molecule, TNF receptor superfamily member 5. | B and T lymphocyte associated. | 0.732 |
CD40 | LTA | ENSPTRP00000068307 | ENSPTRP00000030651 | CD40 molecule, TNF receptor superfamily member 5. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | 0.557 |