STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HNRNPH1HNRNPH1 isoform 31. (472 aa)    
Predicted Functional Partners:
HNRNPA2B1
Heterogeneous nuclear ribonucleoprotein A2/B1.
   
 0.957
HNRNPF
Heterogeneous nuclear ribonucleoprotein F.
  
0.945
HNRNPU
Heterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A).
   
 0.942
HNRNPM
Heterogeneous nuclear ribonucleoprotein M.
   
 0.914
SRSF1
Serine and arginine rich splicing factor 1.
   
 0.910
TRA2B
Transformer 2 beta homolog.
   
 0.890
HNRNPA1
Heterogeneous nuclear ribonucleoprotein A1.
   
 0.887
LOC746306
Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May bind to specific miRNA hairpins. Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1.
   
 0.886
ILF3
Interleukin enhancer binding factor 3, 90kDa.
   
 
 0.882
DDX5
Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]
   
 
 0.877
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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