MIB1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC14	MIB1	ENSPTRP00000070334	ENSPTRP00000093811	CCDC14 isoform 12.	Mindbomb E3 ubiquitin protein ligase 1.	0.712
CCDC14	PCM1	ENSPTRP00000070334	ENSPTRP00000034290	CCDC14 isoform 12.	Pericentriolar material 1.	0.827
CCDC14	PCNT	ENSPTRP00000070334	ENSPTRP00000040619	CCDC14 isoform 12.	PCNT isoform 1.	0.537
DLL1	DLL4	ENSPTRP00000032142	ENSPTRP00000070341	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.932
DLL1	MIB1	ENSPTRP00000032142	ENSPTRP00000093811	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mindbomb E3 ubiquitin protein ligase 1.	0.763
DLL4	DLL1	ENSPTRP00000070341	ENSPTRP00000032142	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.932
DLL4	JAG1	ENSPTRP00000070341	ENSPTRP00000022729	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.410
DLL4	MIB1	ENSPTRP00000070341	ENSPTRP00000093811	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mindbomb E3 ubiquitin protein ligase 1.	0.765
JAG1	DLL4	ENSPTRP00000022729	ENSPTRP00000070341	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.410
JAG1	MIB1	ENSPTRP00000022729	ENSPTRP00000093811	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mindbomb E3 ubiquitin protein ligase 1.	0.806
JAG1	MIB2	ENSPTRP00000022729	ENSPTRP00000062721	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mindbomb homolog 2.	0.561
MIB1	CCDC14	ENSPTRP00000093811	ENSPTRP00000070334	Mindbomb E3 ubiquitin protein ligase 1.	CCDC14 isoform 12.	0.712
MIB1	DLL1	ENSPTRP00000093811	ENSPTRP00000032142	Mindbomb E3 ubiquitin protein ligase 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.763
MIB1	DLL4	ENSPTRP00000093811	ENSPTRP00000070341	Mindbomb E3 ubiquitin protein ligase 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.765
MIB1	JAG1	ENSPTRP00000093811	ENSPTRP00000022729	Mindbomb E3 ubiquitin protein ligase 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.806
MIB1	MIB2	ENSPTRP00000093811	ENSPTRP00000062721	Mindbomb E3 ubiquitin protein ligase 1.	Mindbomb homolog 2.	0.971
MIB1	PCM1	ENSPTRP00000093811	ENSPTRP00000034290	Mindbomb E3 ubiquitin protein ligase 1.	Pericentriolar material 1.	0.833
MIB1	PCNT	ENSPTRP00000093811	ENSPTRP00000040619	Mindbomb E3 ubiquitin protein ligase 1.	PCNT isoform 1.	0.804
MIB1	TANK	ENSPTRP00000093811	ENSPTRP00000092675	Mindbomb E3 ubiquitin protein ligase 1.	TANK isoform 1.	0.904
MIB1	TICAM1	ENSPTRP00000093811	ENSPTRP00000049092	Mindbomb E3 ubiquitin protein ligase 1.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.904