Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNF496ZNF496 isoform 3. (587 aa)    
Predicted Functional Partners:
PGBD1
PGBD1 isoform 1.
    
 
 0.807
ARR3
ARR3 isoform 3.
    
  0.786
ZNF483
ZNF483 isoform 2.
    
 
 0.751
ZSCAN21
ZSCAN21 isoform 1.
   
   0.747
ZSCAN22
Zinc finger and SCAN domain containing 22.
    
   0.736
ZKSCAN4
Zinc finger with KRAB and SCAN domains 4.
    
   0.677
ZNF446
ZNF446 isoform 7.
    
 
 0.642
ZNF618
ZNF618 isoform 4.
    
 
 0.638
ZNF24
Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro (By similarity).
    
   0.635
ZNF396
ZNF396 isoform 3.
    
   0.635
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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