Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFCAB2EF-hand calcium binding domain 2. (162 aa)    
Predicted Functional Partners:
EFHB
EFHB isoform 1.
   
 
 0.691
PPEF1
Serine/threonine-protein phosphatase with EF-hands.
    
 0.674
EFHC2
EF-hand domain containing 2.
   
 
 0.666
GIN1
Gypsy retrotransposon integrase-like protein 1.
   
 
 0.665
TAX1BP1
Tax1-binding protein 1 homolog; Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti- apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade (By similarity).
    
 0.662
EFCAB1
EF-hand calcium binding domain 1.
   
 0.660
CCM2
CCM2 scaffold protein.
    
 0.645
CR201_G0031170-2
AK9 isoform 9.
   
 
 0.643
EFCAB5
EFCAB5 isoform 5.
    
 
 0.638
UCMA
UCMA isoform 1.
      
 0.631
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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