Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)    
Predicted Functional Partners:
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
  
0.991
TSC2
TSC2 isoform 1.
    
 0.986
PDPK1
PDPK1 isoform 1.
  
0.984
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
  
0.984
PHLPP1
PHLPP1 isoform 1.
    
 0.983
TBC1D7
TBC1 domain family member 7.
    
 0.982
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.982
PHLPP2
PHLPP2 isoform 2.
    
 0.981
AKT1S1
AKT1S1 isoform 1.
   
 0.980
TRIB3
TRIB3 isoform 1.
    
0.979
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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