MT1HL1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCS	CR201_G0014586	ENSPPYP00000003493	ENSPPYP00000023568	Copper chaperone for superoxide dismutase.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.507
CCS	LOC100435295	ENSPPYP00000003493	ENSPPYP00000008734	Copper chaperone for superoxide dismutase.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.507
CCS	LOC100936088	ENSPPYP00000003493	ENSPPYP00000017805	Copper chaperone for superoxide dismutase.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.507
CCS	MT1B	ENSPPYP00000003493	ENSPPYP00000008678	Copper chaperone for superoxide dismutase.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.507
CCS	MT1HL1	ENSPPYP00000003493	ENSPPYP00000000080	Copper chaperone for superoxide dismutase.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.465
CCS	MT3	ENSPPYP00000003493	ENSPPYP00000008326	Copper chaperone for superoxide dismutase.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.666
CR201_G0014586	CCS	ENSPPYP00000023568	ENSPPYP00000003493	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Copper chaperone for superoxide dismutase.	0.507
CR201_G0014586	MT1HL1	ENSPPYP00000023568	ENSPPYP00000000080	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.557
CR201_G0014586	MT3	ENSPPYP00000023568	ENSPPYP00000008326	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.455
CR201_G0014586	URM1	ENSPPYP00000023568	ENSPPYP00000022019	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for co [...]	0.518
FBN1	MT1HL1	ENSPPYP00000007315	ENSPPYP00000000080	FBN1 isoform 1.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.410
FBN1	MT3	ENSPPYP00000007315	ENSPPYP00000008326	FBN1 isoform 1.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.468
LOC100435295	CCS	ENSPPYP00000008734	ENSPPYP00000003493	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Copper chaperone for superoxide dismutase.	0.507
LOC100435295	MT1HL1	ENSPPYP00000008734	ENSPPYP00000000080	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.557
LOC100435295	MT3	ENSPPYP00000008734	ENSPPYP00000008326	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.455
LOC100435295	URM1	ENSPPYP00000008734	ENSPPYP00000022019	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for co [...]	0.518
LOC100936088	CCS	ENSPPYP00000017805	ENSPPYP00000003493	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Copper chaperone for superoxide dismutase.	0.507
LOC100936088	MT1HL1	ENSPPYP00000017805	ENSPPYP00000000080	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.557
LOC100936088	MT3	ENSPPYP00000017805	ENSPPYP00000008326	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.455
LOC100936088	URM1	ENSPPYP00000017805	ENSPPYP00000022019	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for co [...]	0.518