| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANK1 | OBSCN | ENSPPYP00000020798 | ENSPPYP00000000139 | Ankyrin-1 isoform X1. | OBSCN isoform 2. | 0.852 |
| ANK1 | TTN | ENSPPYP00000020798 | ENSPPYP00000014501 | Ankyrin-1 isoform X1. | TTN isoform 4. | 0.558 |
| CCDC8 | CUL7 | ENSPPYP00000011350 | ENSPPYP00000018598 | Coiled-coil domain containing 8. | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] | 0.990 |
| CCDC8 | MAPK14 | ENSPPYP00000011350 | ENSPPYP00000018500 | Coiled-coil domain containing 8. | Mitogen-activated protein kinase. | 0.757 |
| CCDC8 | OBSCN | ENSPPYP00000011350 | ENSPPYP00000000139 | Coiled-coil domain containing 8. | OBSCN isoform 2. | 0.971 |
| CCDC8 | TP53 | ENSPPYP00000011350 | ENSPPYP00000008923 | Coiled-coil domain containing 8. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.783 |
| CCDC8 | TTN | ENSPPYP00000011350 | ENSPPYP00000014501 | Coiled-coil domain containing 8. | TTN isoform 4. | 0.628 |
| CR201_G0021858 | MYOM3 | ENSPPYP00000014341 | ENSPPYP00000001994 | NEB isoform 1. | MYOM3 isoform 1. | 0.583 |
| CR201_G0021858 | OBSCN | ENSPPYP00000014341 | ENSPPYP00000000139 | NEB isoform 1. | OBSCN isoform 2. | 0.802 |
| CR201_G0021858 | RYR1 | ENSPPYP00000014341 | ENSPPYP00000011124 | NEB isoform 1. | RYR1 isoform 2. | 0.862 |
| CR201_G0021858 | TCAP | ENSPPYP00000014341 | ENSPPYP00000009530 | NEB isoform 1. | TCAP isoform 1. | 0.577 |
| CR201_G0021858 | TTN | ENSPPYP00000014341 | ENSPPYP00000014501 | NEB isoform 1. | TTN isoform 4. | 0.941 |
| CUL7 | CCDC8 | ENSPPYP00000018598 | ENSPPYP00000011350 | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] | Coiled-coil domain containing 8. | 0.990 |
| CUL7 | MAPK14 | ENSPPYP00000018598 | ENSPPYP00000018500 | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] | Mitogen-activated protein kinase. | 0.636 |
| CUL7 | OBSCN | ENSPPYP00000018598 | ENSPPYP00000000139 | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] | OBSCN isoform 2. | 0.960 |
| CUL7 | TP53 | ENSPPYP00000018598 | ENSPPYP00000008923 | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.924 |
| CUL7 | TTN | ENSPPYP00000018598 | ENSPPYP00000014501 | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] | TTN isoform 4. | 0.751 |
| MAPK14 | CCDC8 | ENSPPYP00000018500 | ENSPPYP00000011350 | Mitogen-activated protein kinase. | Coiled-coil domain containing 8. | 0.757 |
| MAPK14 | CUL7 | ENSPPYP00000018500 | ENSPPYP00000018598 | Mitogen-activated protein kinase. | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] | 0.636 |
| MAPK14 | OBSCN | ENSPPYP00000018500 | ENSPPYP00000000139 | Mitogen-activated protein kinase. | OBSCN isoform 2. | 0.742 |
