STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK18Cyclin-dependent kinase 18; May play a role in signal transduction cascades in terminally differentiated cells. (474 aa)    
Predicted Functional Partners:
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.735
ORC2
Origin recognition complex subunit 2.
 
 
 0.706
CABLES1
CABLES1 isoform 1.
   
 0.691
CDC20
Cell division cycle 20.
   
 0.689
FZR1
FZR1 isoform 4.
   
 0.689
INTU
INTU isoform 1.
   
 0.689
CDC20B
CDC20B isoform 4.
   
 0.689
CCNH
CCNH isoform 4; Belongs to the cyclin family.
    
 0.685
CCNA1
CCNA1 isoform 3; Belongs to the cyclin family.
   
 0.678
CCNA2
CCNA2 isoform 1; Belongs to the cyclin family.
   
 0.678
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.