node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABAT | ACSS1 | ENSPPYP00000008008 | ENSPPYP00000012045 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase. | 0.827 |
ABAT | ACSS2 | ENSPPYP00000008008 | ENSPPYP00000012219 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | ACSS2 isoform 8. | 0.827 |
ABAT | AGXT2 | ENSPPYP00000008008 | ENSPPYP00000017192 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.931 |
ABAT | ALDH6A1 | ENSPPYP00000008008 | ENSPPYP00000006799 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase 6 family member A1. | 0.943 |
ABAT | ALDH9A1 | ENSPPYP00000008008 | ENSPPYP00000000664 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | 0.945 |
ABAT | EHHADH | ENSPPYP00000008008 | ENSPPYP00000016064 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.922 |
ABAT | HADH | ENSPPYP00000008008 | ENSPPYP00000016738 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hydroxyacyl-CoA dehydrogenase. | 0.918 |
ACSF3 | ACSS1 | ENSPPYP00000008636 | ENSPPYP00000012045 | Acyl-CoA synthetase family member 3. | Acetyl-coenzyme A synthetase. | 0.465 |
ACSF3 | ACSS2 | ENSPPYP00000008636 | ENSPPYP00000012219 | Acyl-CoA synthetase family member 3. | ACSS2 isoform 8. | 0.465 |
ACSF3 | ALDH9A1 | ENSPPYP00000008636 | ENSPPYP00000000664 | Acyl-CoA synthetase family member 3. | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | 0.932 |
ACSF3 | EHHADH | ENSPPYP00000008636 | ENSPPYP00000016064 | Acyl-CoA synthetase family member 3. | Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.498 |
ACSF3 | HADH | ENSPPYP00000008636 | ENSPPYP00000016738 | Acyl-CoA synthetase family member 3. | Hydroxyacyl-CoA dehydrogenase. | 0.525 |
ACSS1 | ABAT | ENSPPYP00000012045 | ENSPPYP00000008008 | Acetyl-coenzyme A synthetase. | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.827 |
ACSS1 | ACSF3 | ENSPPYP00000012045 | ENSPPYP00000008636 | Acetyl-coenzyme A synthetase. | Acyl-CoA synthetase family member 3. | 0.465 |
ACSS1 | ACSS2 | ENSPPYP00000012045 | ENSPPYP00000012219 | Acetyl-coenzyme A synthetase. | ACSS2 isoform 8. | 0.904 |
ACSS1 | AGXT2 | ENSPPYP00000012045 | ENSPPYP00000017192 | Acetyl-coenzyme A synthetase. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.827 |
ACSS1 | ALDH6A1 | ENSPPYP00000012045 | ENSPPYP00000006799 | Acetyl-coenzyme A synthetase. | Aldehyde dehydrogenase 6 family member A1. | 0.925 |
ACSS1 | ALDH9A1 | ENSPPYP00000012045 | ENSPPYP00000000664 | Acetyl-coenzyme A synthetase. | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | 0.941 |
ACSS1 | EHHADH | ENSPPYP00000012045 | ENSPPYP00000016064 | Acetyl-coenzyme A synthetase. | Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.881 |
ACSS1 | HADH | ENSPPYP00000012045 | ENSPPYP00000016738 | Acetyl-coenzyme A synthetase. | Hydroxyacyl-CoA dehydrogenase. | 0.892 |