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RGS4 protein (Pongo abelii) - STRING interaction network
"RGS4" - Regulator of G-protein signaling 4 in Pongo abelii
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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RGS4Regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein (By similarity) (302 aa)    
Predicted Functional Partners:
KCNJ3
Potassium inwardly-rectifying channel, subfamily J, member 3 (416 aa)
     
   
  0.709
UHMK1
Serine/threonine-protein kinase Kist; Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family (420 aa)
       
 
  0.685
KCNJ6
G protein-activated inward rectifier potassium channel 2; This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to [...] (306 aa)
     
   
  0.568
RAP1A
RAP1A, member of RAS oncogene family (184 aa)
       
 
  0.555
CRYM
Crystallin, mu (314 aa)
     
   
  0.554
DTNBP1
Dystrobrevin binding protein 1 (351 aa)
           
  0.548
ATE1
Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway (525 aa)
           
  0.547
NTNG2
Netrin G2 (530 aa)
           
  0.545
RGS7BP
Regulator of G protein signaling 7 binding protein (257 aa)
     
 
  0.515
DISC1
Disrupted in schizophrenia 1 (840 aa)
           
  0.500
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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