HDGF protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALYREF	HDGF	ENSPPYP00000009820	ENSPPYP00000000814	Aly/REF export factor.	Heparin binding growth factor.	0.452
ALYREF	NAP1L1	ENSPPYP00000009820	ENSPPYP00000005453	Aly/REF export factor.	Nucleosome assembly protein 1-like 1; Plays a key role in the regulation of embryonic neurogenesis (By similarity). Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development (By similarity). Regulates neurogenesis via the modulation of RASSF10; regulates RASSF10 expression by promoting SETD1A-mediated H3K4 methylation at the RASSF10 promoter (By similarity). Belongs to the nucleosome assembly protein (NAP) family.	0.551
AZU1	HDGF	ENSPPYP00000010429	ENSPPYP00000000814	AZU1 isoform 1.	Heparin binding growth factor.	0.473
AZU1	LOC100438930	ENSPPYP00000010429	ENSPPYP00000013594	AZU1 isoform 1.	MDK isoform 6.	0.487
AZU1	PTN	ENSPPYP00000010429	ENSPPYP00000024477	AZU1 isoform 1.	PTN isoform 1.	0.514
EIF2S2	ENSPPYP00000002879	ENSPPYP00000012209	ENSPPYP00000002879	Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...]	annotation not available	0.543
EIF2S2	HDGF	ENSPPYP00000012209	ENSPPYP00000000814	Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...]	Heparin binding growth factor.	0.562
ENSPPYP00000002879	EIF2S2	ENSPPYP00000002879	ENSPPYP00000012209	annotation not available	Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...]	0.543
ENSPPYP00000002879	HDGF	ENSPPYP00000002879	ENSPPYP00000000814	annotation not available	Heparin binding growth factor.	0.467
FGF2	HDGF	ENSPPYP00000016808	ENSPPYP00000000814	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Heparin binding growth factor.	0.488
HDGF	ALYREF	ENSPPYP00000000814	ENSPPYP00000009820	Heparin binding growth factor.	Aly/REF export factor.	0.452
HDGF	AZU1	ENSPPYP00000000814	ENSPPYP00000010429	Heparin binding growth factor.	AZU1 isoform 1.	0.473
HDGF	EIF2S2	ENSPPYP00000000814	ENSPPYP00000012209	Heparin binding growth factor.	Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...]	0.562
HDGF	ENSPPYP00000002879	ENSPPYP00000000814	ENSPPYP00000002879	Heparin binding growth factor.	annotation not available	0.467
HDGF	FGF2	ENSPPYP00000000814	ENSPPYP00000016808	Heparin binding growth factor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.488
HDGF	LOC100438930	ENSPPYP00000000814	ENSPPYP00000013594	Heparin binding growth factor.	MDK isoform 6.	0.657
HDGF	NAP1L1	ENSPPYP00000000814	ENSPPYP00000005453	Heparin binding growth factor.	Nucleosome assembly protein 1-like 1; Plays a key role in the regulation of embryonic neurogenesis (By similarity). Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development (By similarity). Regulates neurogenesis via the modulation of RASSF10; regulates RASSF10 expression by promoting SETD1A-mediated H3K4 methylation at the RASSF10 promoter (By similarity). Belongs to the nucleosome assembly protein (NAP) family.	0.451
HDGF	NUDT6	ENSPPYP00000000814	ENSPPYP00000016810	Heparin binding growth factor.	NUDT6 isoform 2.	0.487
HDGF	PSIP1	ENSPPYP00000000814	ENSPPYP00000021512	Heparin binding growth factor.	PC4 and SFRS1 interacting protein 1.	0.741
HDGF	PTN	ENSPPYP00000000814	ENSPPYP00000024477	Heparin binding growth factor.	PTN isoform 1.	0.482