| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0049226 | UBA1 | ENSPPYP00000007566 | ENSPPYP00000022706 | UBE2Q2 isoform 2. | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | 0.848 |
| CR201_G0049226 | UBA3 | ENSPPYP00000007566 | ENSPPYP00000015351 | UBE2Q2 isoform 2. | NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down- regulates steroid receptor activity. Necessary for cell cycle progression (By similarity). | 0.612 |
| CR201_G0049226 | UBA5 | ENSPPYP00000007566 | ENSPPYP00000015785 | UBE2Q2 isoform 2. | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates UFM1 and SUMO2. | 0.597 |
| CR201_G0049226 | UBA6 | ENSPPYP00000007566 | ENSPPYP00000016457 | UBE2Q2 isoform 2. | UBA6 isoform 1. | 0.598 |
| CR201_G0049226 | UBA7 | ENSPPYP00000007566 | ENSPPYP00000015508 | UBE2Q2 isoform 2. | UBA7 isoform 1; Belongs to the ubiquitin-activating E1 family. | 0.609 |
| CR201_G0049226 | UBE2H | ENSPPYP00000007566 | ENSPPYP00000020192 | UBE2Q2 isoform 2. | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.631 |
| CR201_G0049226 | UBE2J2 | ENSPPYP00000007566 | ENSPPYP00000002333 | UBE2Q2 isoform 2. | Ubiquitin conjugating enzyme E2 J2. | 0.654 |
| CR201_G0049226 | UBE2Q1 | ENSPPYP00000007566 | ENSPPYP00000000906 | UBE2Q2 isoform 2. | Ubiquitin conjugating enzyme E2 Q1. | 0.758 |
| CR201_G0049226 | UBE2R2 | ENSPPYP00000007566 | ENSPPYP00000021435 | UBE2Q2 isoform 2. | Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. | 0.541 |
| UBA1 | CR201_G0049226 | ENSPPYP00000022706 | ENSPPYP00000007566 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | UBE2Q2 isoform 2. | 0.848 |
| UBA1 | UBA3 | ENSPPYP00000022706 | ENSPPYP00000015351 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down- regulates steroid receptor activity. Necessary for cell cycle progression (By similarity). | 0.635 |
| UBA1 | UBA5 | ENSPPYP00000022706 | ENSPPYP00000015785 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates UFM1 and SUMO2. | 0.626 |
| UBA1 | UBA6 | ENSPPYP00000022706 | ENSPPYP00000016457 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | UBA6 isoform 1. | 0.978 |
| UBA1 | UBA7 | ENSPPYP00000022706 | ENSPPYP00000015508 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | UBA7 isoform 1; Belongs to the ubiquitin-activating E1 family. | 0.929 |
| UBA1 | UBE2H | ENSPPYP00000022706 | ENSPPYP00000020192 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.958 |
| UBA1 | UBE2J2 | ENSPPYP00000022706 | ENSPPYP00000002333 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin conjugating enzyme E2 J2. | 0.793 |
| UBA1 | UBE2Q1 | ENSPPYP00000022706 | ENSPPYP00000000906 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin conjugating enzyme E2 Q1. | 0.709 |
| UBA1 | UBE2QL1 | ENSPPYP00000022706 | ENSPPYP00000017126 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | UBE2QL1 isoform 1. | 0.434 |
| UBA1 | UBE2R2 | ENSPPYP00000022706 | ENSPPYP00000021435 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. | 0.933 |
| UBA3 | CR201_G0049226 | ENSPPYP00000015351 | ENSPPYP00000007566 | NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down- regulates steroid receptor activity. Necessary for cell cycle progression (By similarity). | UBE2Q2 isoform 2. | 0.612 |
