Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RFX5Regulatory factor X5. (616 aa)    
Predicted Functional Partners:
RFXAP
Regulatory factor X associated protein.
    
 0.998
RFXANK
RFXANK isoform 2.
   
 0.998
CIITA
CIITA isoform 1.
    
 0.993
RFX7
Regulatory factor X7.
    
 
 0.866
CCDC82
CCDC82 isoform 1.
      
 0.757
ANKRA2
ANKRA2 isoform 1.
   
 
 0.663
MED23
Mediator complex subunit 23.
      
 0.652
LOC100460187
MHC class II protein; Belongs to the MHC class II family.
    
 
 0.648
CR201_G0056348
RFX8 isoform 2.
      
 0.629
ELF4
ELF4 isoform 1.
      
 0.621
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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