Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (549 aa)    
Predicted Functional Partners:
CR201_G0044279
PIP5K1C isoform 1.
  
 
0.998
PIP5K1B
PIP5K1B isoform 2.
  
 
0.960
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
   
 0.959
PI4KA
PI4KA isoform 1; Belongs to the PI3/PI4-kinase family.
   
 0.952
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.940
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
    
0.937
PI4K2A
Phosphatidylinositol 4-kinase type 2 alpha.
     
 0.937
PIP4K2C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
    
0.934
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
    
0.932
PI4K2B
PI4K2B isoform 1.
     
 0.926
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (12%) [HD]