Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CDC42SE1CDC42 small effector protein 1; Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T- cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages (By similarity); Belongs to the CDC42SE/SPEC family. (79 aa)    
Predicted Functional Partners:
CDC42EP4
CDC42 effector protein 4.
      
 0.719
BAIAP2L1
BAI1 associated protein 2 like 1.
      
 0.657
PNPLA4
PNPLA4 isoform 1.
      
 0.634
CDC42
Cell division cycle 42.
    
 
 0.628
CDC42EP3
CDC42 effector protein 3.
      
 0.619
FLII
FLII isoform 1.
      
 0.594
TMED2
Transmembrane p24 trafficking protein 2.
      
 0.569
CREB3
cAMP responsive element binding protein 3.
   
  
 0.520
BAIAP2
BAI1 associated protein 2.
      
 0.514
SYNGAP1
SYNGAP1 isoform 3.
      
 0.498
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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