Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRUNE1Prune exopolyphosphatase 1. (453 aa)    
Predicted Functional Partners:
HDDC3
HD domain containing 3.
     
 0.901
GSK3B
GSK3B isoform 2; Belongs to the protein kinase superfamily.
    
 
 0.858
GSK3A
Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.
    
 
 0.840
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.726
ENSPPYP00000009291
annotation not available
  
 
 0.588
APRT
APRT isoform 1.
     
 0.580
NME3
Nucleoside diphosphate kinase.
  
 
 0.559
UTP20
UTP20 isoform 1.
      
 0.526
GMPPB
GDP-mannose pyrophosphorylase B.
   
   0.523
MMS19
MMS19 isoform 3.
      
 0.513
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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