Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTSSCTSS isoform 1; Belongs to the peptidase C1 family. (330 aa)    
Predicted Functional Partners:
CD74
CD74 isoform 2.
   
 0.976
CTSL
CTSL isoform 2; Belongs to the peptidase C1 family.
  
0.954
ENSPPYP00000021680
annotation not available
   
 
0.951
BCL2
BCL2 isoform 1.
     
 0.928
IL10RA
Interleukin 10 receptor subunit alpha.
   
 
 0.922
BID
BID isoform 12.
   
 
 0.913
BCL2L1
BCL2L1 isoform 2.
     
 0.910
CREB1
CREB1 isoform 1.
   
 
 0.908
LY86
LY86 isoform 1.
   
  
 0.854
CST3
CST3 isoform 1; Belongs to the cystatin family.
   
 0.805
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.