Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTSL4ADAMTSL4 isoform 1. (994 aa)    
Predicted Functional Partners:
FBN1
FBN1 isoform 1.
    
 0.687
SUOX
SUOX isoform 1.
      
 0.649
B3GLCT
Beta 3-glucosyltransferase.
     
 0.596
MFAP4
Microfibril associated protein 4.
   
  
 0.522
ANKS3
ANKS3 isoform 18.
    
 
 0.488
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
      
 0.486
CPAMD8
CPAMD8 isoform 3.
   
  
 0.477
AQP1
Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
   
   0.470
POFUT2
Protein O-fucosyltransferase 2.
     
 0.458
CR201_G0023722
ADAM11 isoform 1.
      
 0.418
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.