Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECM1Extracellular matrix protein 1. (540 aa)    
Predicted Functional Partners:
SLC39A13
Zinc transporter ZIP13; Acts as a zinc-influx transporter.
      
 0.852
MRPS14
Mitochondrial ribosomal protein S14.
      
 0.843
SLC15A2
SLC15A2 isoform 1.
      
 0.841
DDX52
DDX52 isoform 1.
      
 0.827
ITGAM
ITGAM isoform 1; Belongs to the integrin alpha chain family.
      
 0.825
TAF9B
Transcription initiation factor TFIID subunit 9B; Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity).
      
 0.825
OAS2
OAS2 isoform 1.
      
 0.799
PRL
PRL isoform 1.
      
 0.799
ZBTB44
Zinc finger and BTB domain containing 44.
    
 
 0.782
CR201_G0037575
CLEC17A isoform 1.
     
 0.770
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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