| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AARS1 | EPRS1 | ENSPPYP00000008517 | ENSPPYP00000000215 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | EPRS isoform 1. | 0.885 |
| AARS1 | KARS1 | ENSPPYP00000008517 | ENSPPYP00000008540 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Lysine--tRNA ligase. | 0.804 |
| AARS1 | LARS1 | ENSPPYP00000008517 | ENSPPYP00000017795 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Leucine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.933 |
| AARS1 | LARS2 | ENSPPYP00000008517 | ENSPPYP00000015598 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.823 |
| AARS1 | TARS1 | ENSPPYP00000008517 | ENSPPYP00000017181 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | TARS isoform 1. | 0.771 |
| AARS1 | TARS2 | ENSPPYP00000008517 | ENSPPYP00000001051 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | TARS2 isoform 3. | 0.750 |
| AARS1 | TARS3 | ENSPPYP00000008517 | ENSPPYP00000007749 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | TARSL2 isoform 1. | 0.844 |
| AARS1 | VARS1 | ENSPPYP00000008517 | ENSPPYP00000018404 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | VARS isoform 1; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.780 |
| AARS1 | YARS1 | ENSPPYP00000008517 | ENSPPYP00000001828 | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.933 |
| EPRS1 | AARS1 | ENSPPYP00000000215 | ENSPPYP00000008517 | EPRS isoform 1. | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | 0.885 |
| EPRS1 | KARS1 | ENSPPYP00000000215 | ENSPPYP00000008540 | EPRS isoform 1. | Lysine--tRNA ligase. | 0.999 |
| EPRS1 | LARS1 | ENSPPYP00000000215 | ENSPPYP00000017795 | EPRS isoform 1. | Leucine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
| EPRS1 | LARS2 | ENSPPYP00000000215 | ENSPPYP00000015598 | EPRS isoform 1. | Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.990 |
| EPRS1 | MRPL16 | ENSPPYP00000000215 | ENSPPYP00000003717 | EPRS isoform 1. | 39S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family. | 0.576 |
| EPRS1 | TARS1 | ENSPPYP00000000215 | ENSPPYP00000017181 | EPRS isoform 1. | TARS isoform 1. | 0.757 |
| EPRS1 | TARS2 | ENSPPYP00000000215 | ENSPPYP00000001051 | EPRS isoform 1. | TARS2 isoform 3. | 0.757 |
| EPRS1 | TARS3 | ENSPPYP00000000215 | ENSPPYP00000007749 | EPRS isoform 1. | TARSL2 isoform 1. | 0.757 |
| EPRS1 | VARS1 | ENSPPYP00000000215 | ENSPPYP00000018404 | EPRS isoform 1. | VARS isoform 1; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.998 |
| EPRS1 | YARS1 | ENSPPYP00000000215 | ENSPPYP00000001828 | EPRS isoform 1. | Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
| KARS1 | AARS1 | ENSPPYP00000008540 | ENSPPYP00000008517 | Lysine--tRNA ligase. | Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | 0.804 |
