ENSPPYP00000001065 protein (Pongo abelii) - STRING interaction network

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Score

ENSPPYP00000001065

annotation not available (243 aa)

Predicted Functional Partners:

SF3B2

0.998

SF3B3

0.997

SF3B1

0.997

SF3A2

0.996

SF3B5

0.996

PHF5A

0.990

SNRPA1

0.987

SF3A1

0.986

SF3B6

0.984

DDX42

0.982

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX42	ENSPPYP00000001065	ENSPPYP00000009583	ENSPPYP00000001065	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	annotation not available	0.982
DDX42	PHF5A	ENSPPYP00000009583	ENSPPYP00000013247	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	PHD finger protein 5A.	0.993
DDX42	SF3A1	ENSPPYP00000009583	ENSPPYP00000013060	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	Splicing factor 3a subunit 1.	0.975
DDX42	SF3A2	ENSPPYP00000009583	ENSPPYP00000010484	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	SF3A2 isoform 1.	0.985
DDX42	SF3B1	ENSPPYP00000009583	ENSPPYP00000014574	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	SF3B1 isoform 1.	0.998
DDX42	SF3B2	ENSPPYP00000009583	ENSPPYP00000003511	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	SF3B2 isoform 4.	0.993
DDX42	SF3B3	ENSPPYP00000009583	ENSPPYP00000008511	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...]	0.997
DDX42	SF3B5	ENSPPYP00000009583	ENSPPYP00000019113	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.996
DDX42	SF3B6	ENSPPYP00000009583	ENSPPYP00000014073	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	Splicing factor 3b subunit 6.	0.981
DDX42	SNRPA1	ENSPPYP00000009583	ENSPPYP00000007744	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	Small nuclear ribonucleoprotein polypeptide A.	0.843
ENSPPYP00000001065	DDX42	ENSPPYP00000001065	ENSPPYP00000009583	annotation not available	ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]	0.982
ENSPPYP00000001065	PHF5A	ENSPPYP00000001065	ENSPPYP00000013247	annotation not available	PHD finger protein 5A.	0.990
ENSPPYP00000001065	SF3A1	ENSPPYP00000001065	ENSPPYP00000013060	annotation not available	Splicing factor 3a subunit 1.	0.986
ENSPPYP00000001065	SF3A2	ENSPPYP00000001065	ENSPPYP00000010484	annotation not available	SF3A2 isoform 1.	0.996
ENSPPYP00000001065	SF3B1	ENSPPYP00000001065	ENSPPYP00000014574	annotation not available	SF3B1 isoform 1.	0.997
ENSPPYP00000001065	SF3B2	ENSPPYP00000001065	ENSPPYP00000003511	annotation not available	SF3B2 isoform 4.	0.998
ENSPPYP00000001065	SF3B3	ENSPPYP00000001065	ENSPPYP00000008511	annotation not available	Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...]	0.997
ENSPPYP00000001065	SF3B5	ENSPPYP00000001065	ENSPPYP00000019113	annotation not available	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.996
ENSPPYP00000001065	SF3B6	ENSPPYP00000001065	ENSPPYP00000014073	annotation not available	Splicing factor 3b subunit 6.	0.984
ENSPPYP00000001065	SNRPA1	ENSPPYP00000001065	ENSPPYP00000007744	annotation not available	Small nuclear ribonucleoprotein polypeptide A.	0.987