ENSPPYP00000001065 protein (Pongo abelii) - STRING interaction network

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Score

ENSPPYP00000001065

annotation not available (243 aa)

Predicted Functional Partners:

SF3B2

0.999

SF3A2

0.999

SF3B1

0.999

SF3B3

0.998

SF3B5

0.998

PRPF8

0.997

SF3B6

0.997

BCAS2

0.995

U2AF2

0.993

WDR83

0.990

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCAS2	ENSPPYP00000001065	ENSPPYP00000001168	ENSPPYP00000001065	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	annotation not available	0.995
BCAS2	PRPF8	ENSPPYP00000001168	ENSPPYP00000008763	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	Pre-mRNA processing factor 8.	0.997
BCAS2	SF3A2	ENSPPYP00000001168	ENSPPYP00000010484	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	SF3A2 isoform 1.	0.896
BCAS2	SF3B1	ENSPPYP00000001168	ENSPPYP00000014574	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	SF3B1 isoform 1.	0.884
BCAS2	SF3B2	ENSPPYP00000001168	ENSPPYP00000003511	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	SF3B2 isoform 4.	0.783
BCAS2	SF3B3	ENSPPYP00000001168	ENSPPYP00000008511	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...]	0.893
BCAS2	SF3B5	ENSPPYP00000001168	ENSPPYP00000019113	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.825
BCAS2	SF3B6	ENSPPYP00000001168	ENSPPYP00000014073	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	Splicing factor 3b subunit 6.	0.877
BCAS2	U2AF2	ENSPPYP00000001168	ENSPPYP00000011687	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.727
ENSPPYP00000001065	BCAS2	ENSPPYP00000001065	ENSPPYP00000001168	annotation not available	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	0.995
ENSPPYP00000001065	PRPF8	ENSPPYP00000001065	ENSPPYP00000008763	annotation not available	Pre-mRNA processing factor 8.	0.997
ENSPPYP00000001065	SF3A2	ENSPPYP00000001065	ENSPPYP00000010484	annotation not available	SF3A2 isoform 1.	0.999
ENSPPYP00000001065	SF3B1	ENSPPYP00000001065	ENSPPYP00000014574	annotation not available	SF3B1 isoform 1.	0.999
ENSPPYP00000001065	SF3B2	ENSPPYP00000001065	ENSPPYP00000003511	annotation not available	SF3B2 isoform 4.	0.999
ENSPPYP00000001065	SF3B3	ENSPPYP00000001065	ENSPPYP00000008511	annotation not available	Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...]	0.998
ENSPPYP00000001065	SF3B5	ENSPPYP00000001065	ENSPPYP00000019113	annotation not available	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.998
ENSPPYP00000001065	SF3B6	ENSPPYP00000001065	ENSPPYP00000014073	annotation not available	Splicing factor 3b subunit 6.	0.997
ENSPPYP00000001065	U2AF2	ENSPPYP00000001065	ENSPPYP00000011687	annotation not available	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.993
ENSPPYP00000001065	WDR83	ENSPPYP00000001065	ENSPPYP00000010763	annotation not available	WDR83 isoform 1.	0.990
PRPF8	BCAS2	ENSPPYP00000008763	ENSPPYP00000001168	Pre-mRNA processing factor 8.	Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre- mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19- CDC5L complex may also play a role in the response to DNA damage (DDR).	0.997