PEX11B protein (Pongo abelii) - STRING interaction network

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PEX11B

Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface. (259 aa)

Predicted Functional Partners:

PEX19

0.982

PEX11G

0.975

PEX11A

0.903

PEX13

0.885

PEX12

0.883

PEX3

0.863

PEX14

0.854

PTPRA

0.826

PEX10

0.763

FIS1

0.763

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FIS1	PEX11A	ENSPPYP00000019557	ENSPPYP00000007679	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	PEX11A isoform 3.	0.772
FIS1	PEX11B	ENSPPYP00000019557	ENSPPYP00000001084	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface.	0.763
FIS1	PEX11G	ENSPPYP00000019557	ENSPPYP00000010622	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	PEX11G isoform 2.	0.514
FIS1	PEX12	ENSPPYP00000019557	ENSPPYP00000009205	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.684
FIS1	PEX13	ENSPPYP00000019557	ENSPPYP00000013816	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Peroxisomal biogenesis factor 13.	0.706
FIS1	PEX14	ENSPPYP00000019557	ENSPPYP00000002199	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	PEX14 isoform 2.	0.613
FIS1	PEX19	ENSPPYP00000019557	ENSPPYP00000000743	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.	0.719
FIS1	PEX3	ENSPPYP00000019557	ENSPPYP00000019104	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Peroxisomal biogenesis factor 3.	0.681
PEX10	PEX11A	ENSPPYP00000002293	ENSPPYP00000007679	PEX10 isoform 2.	PEX11A isoform 3.	0.753
PEX10	PEX11B	ENSPPYP00000002293	ENSPPYP00000001084	PEX10 isoform 2.	Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface.	0.763
PEX10	PEX11G	ENSPPYP00000002293	ENSPPYP00000010622	PEX10 isoform 2.	PEX11G isoform 2.	0.673
PEX10	PEX12	ENSPPYP00000002293	ENSPPYP00000009205	PEX10 isoform 2.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.996
PEX10	PEX13	ENSPPYP00000002293	ENSPPYP00000013816	PEX10 isoform 2.	Peroxisomal biogenesis factor 13.	0.979
PEX10	PEX14	ENSPPYP00000002293	ENSPPYP00000002199	PEX10 isoform 2.	PEX14 isoform 2.	0.976
PEX10	PEX19	ENSPPYP00000002293	ENSPPYP00000000743	PEX10 isoform 2.	Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.	0.922
PEX10	PEX3	ENSPPYP00000002293	ENSPPYP00000019104	PEX10 isoform 2.	Peroxisomal biogenesis factor 3.	0.731
PEX11A	FIS1	ENSPPYP00000007679	ENSPPYP00000019557	PEX11A isoform 3.	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	0.772
PEX11A	PEX10	ENSPPYP00000007679	ENSPPYP00000002293	PEX11A isoform 3.	PEX10 isoform 2.	0.753
PEX11A	PEX11B	ENSPPYP00000007679	ENSPPYP00000001084	PEX11A isoform 3.	Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface.	0.903
PEX11A	PEX11G	ENSPPYP00000007679	ENSPPYP00000010622	PEX11A isoform 3.	PEX11G isoform 2.	0.975

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